Expanding Access to Liver Transplant: Why Barnes-Jewish Hospital and WashU Medicine Launched an Adult Living Donor Program - Report - MDSpire

Expanding Access to Liver Transplant: Why Barnes-Jewish Hospital and WashU Medicine Launched an Adult Living Donor Program

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  • June 17, 2026

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Clinical Report: Expanding Access to Liver Transplant with Living Donor Program

Overview

The WashU Medicine and Barnes-Jewish Hospital have established an adult living donor liver transplant program to address the growing gap between liver transplant needs and available organs. This initiative aims to reduce wait times and improve patient outcomes, particularly for those with significant disease burden despite low MELD scores.

Background

{'MASH': 'MAFLD'}

Data Highlights

No numerical data available in the source material.

Key Findings

  • The adult living donor liver transplant program was formally established in 2025 at WashU Medicine and Barnes-Jewish Hospital.
  • MASH accounted for 20.4% of liver transplant wait list registrations in 2023, more than double the share from a decade ago.
  • Living donation can significantly reduce time on the waiting list and prevent further hepatic decompensation.
  • Patients with hepatocellular carcinoma and colorectal liver metastases may benefit from living donor transplantation despite low MELD scores.
  • The program utilizes advanced imaging technologies for surgical planning and donor selection protocols to ensure safety and appropriateness.

Clinical Implications

Healthcare professionals should consider referring patients with significant liver disease for evaluation of living donor transplantation, especially those with low MELD scores. The establishment of living donor programs can enhance patient access to timely transplants and improve overall survival outcomes.

Conclusion

The launch of the adult living donor liver transplant program at WashU Medicine and Barnes-Jewish Hospital represents a significant advancement in addressing the liver transplant shortage. This initiative not only expands donor options but also aims to improve patient outcomes in a challenging clinical landscape.

Related Resources & Content

  1. Barnes-Jewish, Advancing Liver Transplant Innovation, 2023 -- Video discussion on liver transplant advancements
  2. Barnes-Jewish, A Wider Organ Donor Pool Saves Lives, 2023 -- Case study on organ donation
  3. Keck Medicine of USC, Rare Kidney-Liver Paired Exchange, 2023 -- Unique living-donor transplant case
  4. AASLD, AASLD and AST Announce Two New Practice Guidelines, 2025 -- Updated guidelines on liver transplantation
  5. PubMed, Comparative Outcomes of Living and Deceased Donor Liver Transplantation, 2026 -- Systematic review on transplant outcomes
  6. keck medicine of usc — Liver Transplants Reach Record Highs in the U.S. What’s Driving Growth?
  7. AASLD and AST Announce Two New Practice Guidelines | AASLD
  8. Comparative Outcomes of Living and Deceased Donor Liver Transplantation in Adults: A Systematic Review and Meta-Analysis - PubMed
  9. OPTN/SRTR 2024 Annual Data Report: Overview of US Solid Organ Transplantation

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