Assessment of growth and pain trajectories for children and adolescents receiving chemotherapy for acute lymphoblastic leukemia in Northern Thailand using group-based trajectory modeling - Report - MDSpire
Advertisement
Assessment of growth and pain trajectories for children and adolescents receiving chemotherapy for acute lymphoblastic leukemia in Northern Thailand using group-based trajectory modeling
Evaluation of Growth Patterns and Pain Experiences in Pediatric Chemotherapy Patients
Overview
This study evaluated bodyweight, BMI, and pain trajectories in pediatric patients with acute lymphoblastic leukemia (ALL) undergoing chemotherapy. It identified significant associations between age, risk group, and ethnicity with growth and pain outcomes.
Background
Childhood leukemia, particularly acute lymphoblastic leukemia (ALL), poses significant health challenges, including growth and pain issues during treatment. Understanding these trajectories is essential. This study contributes to the limited research on growth and pain patterns in pediatric ALL patients.
Data Highlights
Finding
Details
Bodyweight Trajectories
Four latent classes identified; two-thirds in slightly low-normal group.
BMI Changes
94% classified as healthy weight; minority overweight/obese.
Pain Levels
High pain prevalent in 75% initially; declined over time.
Age Association
Older age linked to higher bodyweight and pain trajectory.
Ethnicity Impact
Thai ethnicity associated with mild pain and higher BMI.
Key Findings
Two-thirds of patients classified in slightly low-normal bodyweight group.
High-bodyweight group more likely in older (6-15 years) and high-risk ALL patients.
94% of patients classified as healthy weight for BMI; overweight/obese mainly in older patients.
High pain levels initially observed in 75% of patients, with a decline over time.
Thai ethnicity linked to mild pain experiences.
Clinical Implications
Clinicians should monitor growth and pain trajectories in pediatric ALL patients, particularly focusing on older patients and those in high-risk groups.
Conclusion
The study highlights the importance of tracking growth and pain in pediatric ALL patients, revealing significant associations with age, risk group, and ethnicity.
