Relationship between endometrial VFI values detected by three-dimensional power Doppler ultrasound and pregnancy outcomes in FET patients and prediction of the optimal VFI range—a retrospective cohort study - Report - MDSpire
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Relationship between endometrial VFI values detected by three-dimensional power Doppler ultrasound and pregnancy outcomes in FET patients and prediction of the optimal VFI range—a retrospective cohort study
Clinical Report: Association of Endometrial Vascular Flow Index with Pregnancy Outcomes
Overview
Revise to specify the significance of the correlation and clarify the optimal VFI threshold.
Background
The assessment of endometrial receptivity is crucial for successful embryo implantation in assisted reproductive technology (ART). Endometrial blood flow, as measured by VFI using three-dimensional energy Doppler ultrasound, may provide insights into the likelihood of successful pregnancy outcomes. Understanding the optimal VFI range could enhance clinical decision-making in FET procedures.
Data Highlights
Group
VFI Range
Abortion Rate
Group 1
VFI ≤ 0.041
High
Group 2
0.041 < VFI ≤ 0.165
Moderate
Group 3
0.165 < VFI ≤ 0.461
Low
Group 4
VFI > 0.461
Lowest
Key Findings
Groups with higher VFI values (Group 3 and Group 4) had significantly lower abortion rates compared to Group 1 (p < 0.05).
Adjusted odds ratios for Groups 3 and 4 were 0.210 and 0.227, indicating a reduced risk of abortion.
A significant linear negative correlation was found between VFI values and abortion rates (p < 0.05).
The threshold VFI value identified was 0.1698045, above which abortion rates decreased.
Three-dimensional energy Doppler ultrasound is effective in measuring endometrial blood flow for assessing receptivity.
Clinical Implications
Align the VFI reference point with the study's identified threshold of 0.1698045.
Conclusion
The study underscores the importance of endometrial VFI as a predictive indicator for miscarriage risk in FET patients. Establishing an optimal VFI range can enhance clinical practices and improve pregnancy outcomes.
