Insulinoma in pregnancy: a case report and literature review of diagnostic challenges, multidisciplinary management, and therapeutic dilemmas - Report - MDSpire
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Insulinoma in pregnancy: a case report and literature review of diagnostic challenges, multidisciplinary management, and therapeutic dilemmas
Clinical Report: Insulinoma in Expectant Mothers: A Case Study and Review
Overview
This report details a rare case of insulinoma diagnosed in a pregnant woman, highlighting diagnostic challenges and management complexities. A multidisciplinary team approach was essential for balancing maternal and fetal health during treatment.
Background
Insulinoma during pregnancy is extremely rare, with fewer than 30 cases documented globally. The condition poses significant risks due to overlapping symptoms with normal pregnancy, leading to delayed diagnosis. Effective management is crucial to mitigate risks for both the mother and fetus.
Data Highlights
No numerical data available.
Key Findings
Insulinoma diagnosis in pregnancy is complicated by overlapping gestational symptoms.
Biochemical evaluation revealed inappropriately elevated insulin and C-peptide levels during hypoglycemia.
Magnetic resonance imaging (MRI) was utilized to identify a pancreatic lesion consistent with insulinoma.
A multidisciplinary team approach was critical for managing the case, balancing treatment risks.
Medical therapy with octreotide achieved partial glycemic control during pregnancy.
Postpartum treatment included endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) for glycemic stabilization.
Clinical Implications
Healthcare providers should maintain a high index of suspicion for insulinoma in pregnant patients presenting with hypoglycemia. A multidisciplinary approach is essential for effective management, considering both maternal and fetal health outcomes.
Conclusion
This case underscores the diagnostic challenges of insulinoma in pregnancy and the necessity for individualized, multidisciplinary care. Ongoing evaluation and adaptation of treatment strategies are vital for optimizing outcomes.
