The clinical value of analyzing predictive models for gastric function and gastric organic lesions - Report - MDSpire

The clinical value of analyzing predictive models for gastric function and gastric organic lesions

  • By

  • Youlin Song

  • Yi Hu

  • Kang Wang

  • Yanhua Zhu

  • Yang Wang

  • Tao Liu

  • Lihao Wu

  • Xingxiang He

  • Lei Wu

  • June 15, 2026

  • 0 min

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Clinical Report: Evaluating the Clinical Significance of Predictive Models for Gastric Function and Organic Lesions

Overview

This study evaluates the clinical value of predictive models for gastric function and organic lesions using data from 1,677 patients.

Background

Gastric cancer remains a significant health concern, particularly in regions with high incidence rates like China. Early detection and intervention are crucial for improving outcomes, yet traditional screening methods face limitations.

Data Highlights

ModelSensitivitySpecificityPositive Predictive ValueNegative Predictive ValueAUCYouden Index
Gastric Function Prediction Model91.16%39.18%83.27%57.14%0.7020.303
Gastric Organic Lesion Prediction Model89.55%33.22%70.86%63.67%0.6720.228

Key Findings

The gastric function prediction model achieved a sensitivity of 91.16% and specificity of 39.18%. The gastric organic lesion prediction model had a sensitivity of 89.55% and specificity of 33.22%. Both models demonstrated good predictive performance with AUC values of 0.702 and 0.672, respectively.

Clinical Implications

The findings indicate the predictive models' potential in identifying gastric function abnormalities and organic lesions.

Conclusion

The study validates the predictive models for gastric function and organic lesions.

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  4. Surgical Endoscopy, 2025 -- Effectiveness of Endoscopic Treatment for T1b Gastric Cancer Patients and Development of a Prognostic Model: A Retrospective Cohort and Multicenter Validation Study
  5. Thieme, 2025 -- Management of epithelial precancerous conditions and guidelines
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  7. Frontiers, 2024 -- Establishment and validation of a nomogram model for early diagnosis of gastric cancer: a large-scale cohort study
  8. NCI, 2024 -- Stomach (Gastric) Cancer Screening (PDQ®)
  9. Article published online: 2025-03-20GuidelineThiemeManagement of epithelial precancerous conditions and
  10. Article published online: 2025-01-29
  11. Frontiers | Establishment and validation of a nomogram model for early diagnosis of gastric cancer: a large-scale cohort study
  12. Stomach (Gastric) Cancer Screening (PDQ®) - NCI
  13. Official journal of the American College of Gastroenterology | ACG

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