Balancing patients’ benefits and risks in computed tomography: a European Society of Radiology ‘EuroSafe Imaging’ viewpoint - Report - MDSpire

Balancing patients’ benefits and risks in computed tomography: a European Society of Radiology ‘EuroSafe Imaging’ viewpoint

  • By

  • John Damilakis

  • Claudio Granata

  • Elmar Kotter

  • Boris Brkljacic

  • August 9, 2025

  • 0 min

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Clinical Report: Evaluating CT Benefits and Risks from EuroSafe Imaging Insights

Overview

Computed tomography (CT) is a vital diagnostic tool but carries a small risk of radiation-induced cancer, with an estimated 103,000 future cancers projected from U.S. CT scans in 2023. The EuroSafe Imaging Initiative emphasizes justification, optimization, and balanced risk communication to maximize clinical benefits while minimizing radiation exposure.

Background

CT imaging has become indispensable in modern medicine, offering critical diagnostic information across numerous clinical scenarios. However, CT exposes patients to ionizing radiation, which has been linked to an increased cancer risk, particularly in children. Large cohort studies have confirmed a small but significant association between CT exposure and subsequent cancer incidence, reinforcing the need for cautious use. Adult data are less definitive due to higher baseline cancer rates and longer latency periods for solid tumors.

Data Highlights

MetricValueSource
Projected future cancers from CT scans in U.S. (2023)~103,000[1]
Percentage of all new cancers annually~5%[1]
Projected cancers from CT scans in 2007~29,000[2]
Radiation-attributable leukemia/lymphoma risk in children per 10,000 scans1–2 cases within 12 years[3]

Key Findings

  • CT scans contribute to a measurable cancer burden, with projections indicating a substantial increase in radiation-induced cancers compared to previous estimates.
  • Children exposed to CT radiation have a small but statistically significant increased risk of leukemia and brain tumors.
  • Adult cancer risk from CT is harder to quantify epidemiologically due to higher baseline risks and longer tumor latency.
  • Justification of CT exams varies widely, highlighting the need for strict adherence to clinical indications to avoid unnecessary radiation.
  • Modern CT technologies and dose optimization protocols can significantly reduce radiation exposure without compromising diagnostic quality.
  • Effective communication strategies are essential to inform patients about risks without causing undue alarm, emphasizing the low absolute risk and the benefits of appropriate imaging.

Clinical Implications

Clinicians should rigorously apply justification principles to ensure CT scans are performed only when clinically necessary and optimize protocols to minimize radiation dose. Collaboration between radiologists and referring physicians is vital to balance diagnostic benefits against potential risks. Transparent, balanced patient communication about radiation risks and safety measures can maintain trust and support informed decision-making.

Conclusion

The EuroSafe Imaging Initiative reinforces the importance of justification, optimization, and clear communication in CT imaging to safeguard patients while preserving the modality's diagnostic value. Ongoing efforts to reduce unnecessary scans and lower radiation doses remain critical as CT utilization continues to grow.

References

  1. Berrington de González et al. 2023 -- Projected Cancer Risks from CT Scans in the U.S.
  2. Brenner & Hall 2007 -- Estimated Cancer Risks from CT Scans
  3. Pearce et al. 2012 -- Cancer Risk in Children after CT Exposure
  4. European Commission 2022 -- Justification of CT Examinations in EU Member States
  5. Smith-Bindman et al. 2019 -- Media Misinterpretation of CT Radiation Risks
  6. World Health Organization 2021 -- Communication Tools for Imaging Risks

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