Exploring Health Literacy Profiles in Breast Cancer Patients and Assessing Associated Quality of Life Differences - Report - MDSpire

Exploring Health Literacy Profiles in Breast Cancer Patients and Assessing Associated Quality of Life Differences

  • By

  • Mengwei Jiang

  • Bei Wu

  • Yi Liu

  • Detian Liu

  • Xiaoye Chen

  • Ting Shu

  • Zijun Yuan

  • Linxin Xie

  • Hongzhen Xie

  • April 23, 2026

  • 0 min

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Health Literacy Profiles in Breast Cancer Patients and Quality of Life Differences

Overview

This study identified three distinct health literacy profiles among breast cancer patients—low, moderate, and high—and demonstrated significant differences in quality of life across these groups. Educational attainment, caregiver status, and having healthcare-affiliated acquaintances were key factors associated with health literacy levels.

Background

Breast cancer is the most common cancer among women globally, with significant mortality and morbidity. Despite improved survival rates, patients often experience compromised quality of life due to disease and treatment-related challenges. Health literacy, defined as the ability to obtain, understand, and use health information, is a critical determinant of quality of life in this population. Prior research has not fully explored heterogeneity in health literacy or its direct relationship with quality of life among breast cancer patients.

Data Highlights

Health Literacy ProfilePercentage of PatientsQuality of Life Scores
Low Health Literacy9.2%Significantly lower overall and subscale scores
Moderate Health Literacy29.3%Intermediate quality of life scores
High Health Literacy61.5%Highest overall and subscale quality of life scores

Key Findings

  • Three latent health literacy profiles were identified: low (9.2%), moderate (29.3%), and high (61.5%).
  • Higher educational attainment, being a primary caregiver, and having relatives or friends in healthcare were significantly associated with higher health literacy profiles (P < 0.05).
  • Quality of life scores, including all subscales, differed significantly across the three health literacy profiles (P < 0.05).
  • Patients with higher health literacy demonstrated better comprehension, health behaviors, and consequently improved quality of life.
  • Latent profile analysis effectively captured heterogeneity in health literacy among breast cancer patients.

Clinical Implications

Clinicians should assess health literacy levels in breast cancer patients to identify those at risk of poorer quality of life. Tailored interventions targeting specific health literacy profiles can optimize patient education and support, potentially improving treatment adherence and outcomes. Incorporating caregiver involvement and leveraging social healthcare networks may enhance health literacy and patient well-being.

Conclusion

Distinct health literacy profiles exist among breast cancer patients and are significantly linked to quality of life differences. Targeted, profile-based interventions are essential to enhance health literacy and improve patient outcomes.

References

  1. Chinese Anti-Cancer Association 2024 -- Guidelines and Standards for Diagnosis and Treatment of Breast Cancer (2024 Edition)
  2. Mplus 8.3 -- Latent Profile Analysis Software
  3. SPSS 27.0 -- Statistical Analysis Software

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