Outcomes of Selective Laser Trabeculoplasty as Initial Treatment for Glaucoma: A Retrospective Analysis from Enugu, Nigeria - Report - MDSpire
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Outcomes of Selective Laser Trabeculoplasty as Initial Treatment for Glaucoma: A Retrospective Analysis from Enugu, Nigeria

  • By

  • Nkiru Nwamaka Kizor-Akaraiwe

  • Suhanyah Okeke

  • Chukwu Oko

  • Nkechi Uche

  • Obinna Jude Shiweobi

  • February 14, 2026

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Outcomes of Selective Laser Trabeculoplasty as Initial Treatment for Glaucoma

Overview

This study evaluates the efficacy of Selective Laser Trabeculoplasty (SLT) as a primary treatment for open-angle glaucoma in a Nigerian cohort. Results indicate significant intraocular pressure reduction, supporting SLT's role as a viable first-line therapy in this population.

Background

Glaucoma is a leading cause of irreversible blindness, necessitating effective management strategies to lower intraocular pressure (IOP). Traditional treatments often face challenges such as poor adherence and side effects, particularly in developing regions. SLT has emerged as a promising alternative, offering effective IOP reduction with fewer complications.

Data Highlights

ParameterValue
Sample Size93 eyes from 50 patients
Follow-up DurationMinimum 3 months
IOP Reduction Range30-40% at 12 months

Key Findings

  • SLT effectively reduced IOP in treatment-naïve patients with open-angle glaucoma.
  • Mean IOP reductions at 12 months ranged from 30% to 40%.
  • Over 80% of patients maintained a reduction of 20% in IOP one year post-treatment.
  • SLT is gaining acceptance as a primary treatment option despite barriers such as cost and equipment availability.
  • This study is the first to assess SLT in treatment-naïve eyes in southeastern Nigeria.

Clinical Implications

The findings support the use of SLT as a first-line treatment for open-angle glaucoma, particularly in regions with limited access to medications. Clinicians should consider SLT for patients who may struggle with adherence to topical therapies.

Conclusion

SLT demonstrates significant efficacy in lowering IOP in a Nigerian cohort, reinforcing its potential as a primary treatment for glaucoma. Further studies are warranted to explore its long-term outcomes in diverse populations.

Related Resources & Content

  1. Gus-Gazzard et al., Ophthalmology Management, 2024 -- New Analysis of LiGHT Finds SLT Significantly Slows Glaucoma Progression Compared to Drops
  2. NICE, Glaucoma: diagnosis and management, 2022 -- NICE guideline NG81
  3. European Glaucoma Society, 2026 -- Managing Glaucoma With SLT
  4. Glaucoma Physician — Current Status of Excimer Laser Trabeculostomy Recommendations
  5. Optometric Management — Managing Glaucoma With SLT
  6. Ophthalmology Management — SLT earns a place as first-line therapy
  7. Current Status of Excimer Laser Trabeculostomy Recommendations
  8. Managing Glaucoma With SLT
  9. SLT earns a place as first-line therapy
  10. Glaucoma: diagnosis and
  11. European Glaucoma Society
  12. Safety and efficacy of laser trabeculoplasty compared to drug therapy for the management of open-angle glaucoma: systematic review and meta-analysis study - PubMed

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