The effect of non-immersive virtual reality on upper limb motor function and activities of daily living in stroke patients: a systematic review and meta-analysis - Report - MDSpire

The effect of non-immersive virtual reality on upper limb motor function and activities of daily living in stroke patients: a systematic review and meta-analysis

  • By

  • Mingchen Wang

  • Guan Wang

  • Shulei Wang

  • Xueyan Wang

  • Huijiao Lin

  • June 30, 2026

  • 0 min

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Clinical Report: Impact of Non-Immersive Virtual Reality on Stroke Recovery

Overview

This systematic review and meta-analysis found that non-immersive virtual reality (NIVR) significantly improves upper limb motor function and activities of daily living in stroke survivors when combined with conventional therapy.

Background

Stroke is a major cause of disability, with upper limb dysfunction affecting a significant proportion of survivors. Conventional rehabilitation methods often face challenges such as low patient adherence and limited access.

Data Highlights

Outcome MeasureMean Difference (MD)95% Confidence Interval (CI)
Fugl-Meyer Assessment for Upper Extremity (FMA-UE)5.40(1.58, 9.22)
Box and Block Test (BBT)4.57(0.35, 8.79)
Functional Independence Measure (FIM)5.99(2.27, 9.71)
Barthel Index/Modified Barthel Index (BI/MBI)5.47(0.30, 10.63)

Key Findings

  • NIVR significantly improved upper limb motor function as measured by FMA-UE and BBT.
  • Functional Independence Measure (FIM) scores showed significant improvement with NIVR.
  • Barthel Index/Modified Barthel Index (BI/MBI) analysis indicated a marginally significant effect.
  • Subgroup analyses for BI and MBI did not reach statistical significance, suggesting limited power.
  • Three studies had dose imbalances, which may affect the interpretation of results.
  • The review included 12 randomized controlled trials with a total of 498 stroke patients.

Clinical Implications

Clinicians should consider the potential benefits of incorporating NIVR into rehabilitation programs.

Conclusion

NIVR appears to enhance upper limb function and activities of daily living in stroke survivors.

Related Resources & Content

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  5. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association
  6. Effects of virtual reality with different modalities on upper limb recovery: a systematic review and network meta-analysis on optimizing stroke rehabilitation
  7. A randomized controlled trial of timing and dosage of upper extremity rehabilitation in virtual environments in persons with subacute stroke
  8. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association
  9. Effects of virtual reality with different modalities on upper limb recovery: a systematic review and network meta-analysis on optimizing stroke rehabilitation
  10. A randomized controlled trial of timing and dosage of upper extremity rehabilitation in virtual environments in persons with subacute stroke - PMC

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