Adverse events and clinical risk factors during intrahospital transport of critically ill neonates: a prospective pilot study at a tertiary center in Vietnam - Report - MDSpire
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Adverse events and clinical risk factors during intrahospital transport of critically ill neonates: a prospective pilot study at a tertiary center in Vietnam
Clinical Risks and Adverse Outcomes Associated with Intrahospital Transport of Critically Ill Neonates
Overview
This pilot study evaluates the safety of intrahospital transport for critically ill neonates, reporting that over half of transport events were classified as unsafe, primarily due to hypothermia. Surgical indications were identified as significant risk factors for adverse outcomes during transport.
Background
Intrahospital transport is a common necessity in neonatal intensive care, yet it poses risks of physiological instability and adverse events. Data from low- and middle-income countries are limited.
Data Highlights
Outcome
Count
Percentage
Unsafe Transport (Primary Definition)
71
51.4%
Unsafe Transport (Secondary Definition)
44
31.9%
Adverse Events
100
-
Moderate Hypothermia
34
-
Mild Hypothermia
40
-
Key Findings
51.4% of transport events were classified as unsafe under the primary definition.
Hypothermia was the most frequent adverse event, occurring in 74% of unsafe transports.
Surgical indication was the strongest independent predictor of unsafe transport outcomes.
Moderate hypothermia was associated with an escalation in support needs (41.2% vs. 18.6%).
Transport significantly increased FiO2 and reduced SpO2/FiO2 ratios.
Clinical Implications
Healthcare providers should prioritize thermal protection measures during intrahospital transport of critically ill neonates, particularly for surgical cases. Standardized protocols for temperature monitoring and assessment post-transport are essential to mitigate risks.
Conclusion
The study reports frequent adverse events during intrahospital transport of critically ill neonates, with surgical cases presenting the highest risk.
A prespecified exploratory analysis of the FIND-CKD clinical trial examined kidney function, albuminuria, and kidney failure outcomes in 903 patients with glomerular diseases.
