Comparison of Swept-Source Optical Coherence Tomography and Dual Scheimpflug Placido Analyzer in Healthy Eyes, Suspected Keratoconus, and Diagnosed Keratoconus Cases - Report - MDSpire

Comparison of Swept-Source Optical Coherence Tomography and Dual Scheimpflug Placido Analyzer in Healthy Eyes, Suspected Keratoconus, and Diagnosed Keratoconus Cases

  • By

  • Mohd-Asyraaf Abdul-Kadir

  • Muhammad Adri Mohamed Shafit

  • Adzura Salam

  • Khairidzan Mohd Kamal

  • March 28, 2026

  • 0 min

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Clinical Report: Comparison of Swept-Source OCT and Dual Scheimpflug Analyzer

Overview

This study compares the performance of Swept-Source Optical Coherence Tomography (SS-OCT) and Dual Scheimpflug Placido Analyzer in assessing corneal parameters in healthy eyes and those with suspected or diagnosed keratoconus (KC). The findings indicate that while both devices are effective, their interchangeability is limited, particularly in KC cases.

Background

Keratoconus (KC) is a progressive corneal disease that can lead to significant visual impairment if not detected early. Accurate diagnosis is crucial for timely interventions, such as corneal cross-linking, which can halt disease progression. Advances in imaging technologies, including SS-OCT and dual Scheimpflug systems, have enhanced the ability to detect KC at earlier stages.

Data Highlights

No numerical data available in the source material.

Key Findings

  • Both ANTERION (SS-OCT) and GALILEI (dual Scheimpflug) are effective in measuring corneal parameters.
  • ANTERION shows good intra-session repeatability for keratometry parameters.
  • GALILEI has high repeatability in ocular biometric measurements and agreement with other devices.
  • Comparative studies indicate limited agreement between SS-OCT and dual Scheimpflug systems in keratoconus cases.
  • Device-specific algorithms may influence the accuracy of measurements in KC.

Clinical Implications

Clinicians should be aware of the strengths and limitations of both SS-OCT and dual Scheimpflug systems when diagnosing keratoconus. Understanding the differences in measurement agreement can guide clinical decision-making and patient management strategies.

Conclusion

The study highlights the importance of using appropriate imaging modalities for the diagnosis of keratoconus, emphasizing that while both devices are valuable, they are not interchangeable, particularly in clinical settings involving keratoconus.

References

  1. Glaucoma Physician, 2022 -- Swept-source OCT in Primary Angle-closure Disease an Effective Diagnostic Recommendations
  2. Retinal Physician, 2019 -- Evolving Technology and New Terminology in Swept-Source OCT Angiography for Diabetic Retinopathy
  3. Ophthalmology Management, 2019 -- Seeing the Unseen with Swept-Source OCT
  4. AAO Corneal Ectasia Guideline Summary 2024 Preferred Practice Pattern - Guideline Central
  5. Agreement between a swept-source optical coherence tomography and dual Scheimpflug Placido analyser in healthy, keratoconus suspect and keratoconus eyes - PMC
  6. Ophthalmology Management — Beyond Traditional Vision Measures
  7. AAO Corneal Ectasia Guideline Summary 2024 Preferred Practice Pattern - Guideline Central
  8. Agreement between a swept-source optical coherence tomography and dual Scheimpflug Placido analyser in healthy, keratoconus suspect and keratoconus eyes - PMC
  9. Frontiers | Digital transformation of care for keratoconus patients: ML modeling structural outcomes of corneal collagen cross-linking

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