Construction of a sensitive indicator evaluation system for sepsis care quality: a three-stage mixed-method Delphi study - Report - MDSpire

Construction of a sensitive indicator evaluation system for sepsis care quality: a three-stage mixed-method Delphi study

  • By

  • Chen Huang

  • Huan Liu

  • Wenwen Qi

  • Shuyuan Zhao

  • Jinghua Xu

  • Feng Jing

  • Erzhen Chen

  • May 4, 2026

  • 0 min

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Clinical Report: Development of a Comprehensive Evaluation Framework for Sepsis Care Quality

Overview

This study presents a novel framework for assessing sepsis care quality in China, developed through a mixed-methods Delphi study. It identifies a comprehensive set of nursing-sensitive quality indicators (NSQIs) aimed at improving clinical outcomes in sepsis management.

Background

Sepsis is a critical global health issue, leading to significant morbidity and mortality. Effective management relies on high-quality care, which is influenced by the unique healthcare context in China, including nurse-to-patient ratios and resource distribution. The absence of a tailored assessment framework for sepsis care quality in China highlights the need for this study.

Data Highlights

Indicator TypeCount
Primary Indicators3
Secondary Indicators9
Tertiary Indicators30

Key Findings

  • Two rounds of expert consultation achieved a 100% questionnaire return rate.
  • The expert authority coefficient Cr was 0.95 and 0.96 across the two rounds, indicating high reliability.
  • Significant consensus was reached with a coordination coefficient (Kendall W) of 0.120-0.316 (p < 0.001) in the first round.
  • A total of 42 nursing-sensitive quality indicators were established for sepsis care quality evaluation.
  • The NSQIs focus on three dimensions: importance, rationality, and feasibility.

Clinical Implications

The developed NSQIs provide a structured approach for evaluating sepsis care quality, which can enhance nursing practices and patient outcomes. Implementing this framework may facilitate adherence to evidence-based guidelines and improve overall sepsis management in clinical settings.

Conclusion

This study establishes a comprehensive evaluation framework for sepsis care quality in China, addressing a critical gap in the current healthcare system. The findings underscore the importance of context-specific quality indicators in improving sepsis management.

References

  1. Intensive Care Medicine, 2024 -- Guidelines for Sepsis Management in Adults within Resource-Constrained Environments: A Global Consensus Derived from the Delphi Technique
  2. Intensive Care Medicine, 2022 -- Creation of a Set of Quality Metrics to Enhance ICU Care in Low- and Middle-Income Nations
  3. Infection, 2022 -- Evaluating the Effects of a Sepsis Quality Improvement Initiative in the Emergency Department: A Pre- and Post-Intervention Analysis
  4. Infection, 2018 -- Establishing a Minimum Quality Standard for Pre-Clinical Sepsis Research (MQTiPSS): A Global Expert Consensus to Enhance Animal Models in Sepsis
  5. Die Anaesthesiologie, 2025 -- Update 2025 der S3-Leitlinie: „Sepsis – Prävention, Diagnose, Therapie und Nachsorge“
  6. Update 2025 der S3-Leitlinie: „Sepsis – Prävention, Diagnose, Therapie und Nachsorge“ | Die Anaesthesiologie
  7. Door-to-antibiotic time and mortality in patients with sepsis: Systematic review and meta-analysis - ScienceDirect
  8. Severe Sepsis and Septic Shock:

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