Prospective Clinical Evaluation of a Novel Repositionable Plastic Stent for Endosonography-Guided Hepaticogastrostomy With or Without Antegrade Stenting (With Videos) - Report - MDSpire

Clinical Assessment of a New Repositionable Plastic Stent for Endosonography-Guided Hepaticogastrostomy With or Without Antegrade Stenting (Including Videos)

  • By

  • Shuntaro Mukai

  • Atsushi Sofuni

  • Takayoshi Tsuchiya

  • Reina Tanaka

  • Ryosuke Tonozuka

  • Yukitoshi Matsunami

  • Kazumasa Nagai

  • Hiroyuki Kojima

  • Hirohito Minami

  • Noriyuki Hirakawa

  • Kyoko Asano

  • Kento Shionoya

  • Takao Itoi

  • July 19, 2026

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Clinical Assessment of a New Repositionable Plastic Stent for EUS-HGS

Overview

This study evaluates the efficacy and safety of a novel repositionable plastic stent (PS) designed for endosonography-guided hepaticogastrostomy (EUS-HGS) in patients with malignant or benign biliary disease.

Background

Endosonography-guided hepaticogastrostomy (EUS-HGS) is an alternative for managing obstructive jaundice in patients with unresectable malignant biliary obstruction. The development of dedicated stents that enhance the safety and efficacy of EUS-HGS is crucial, particularly given concerns regarding adverse events such as bile leakage and stent migration.

Data Highlights

No numerical data or trial data were provided in the source material.

Key Findings

  • The repositionable PS delivery system allows for pullback in difficult cases.
  • The stent design includes features to prevent migration or dislodgement.
  • Insertion performance of the repositionable PS is comparable to conventional pusher-type PS.
  • The study was conducted at Tokyo Medical University with a prospective design.
  • Patients included those with malignant biliary obstruction or benign biliary disease.

Clinical Implications

The repositionable PS may offer a safer and more effective option for EUS-HGS, potentially reducing the risk of complications associated with traditional stents. Clinicians should consider this new technology in appropriate cases of biliary obstruction.

Conclusion

The novel repositionable plastic stent shows promise in enhancing the safety and efficacy of EUS-HGS procedures. Further studies may be warranted to confirm these findings in larger populations.

Related Resources & Content

  1. ASGE, American Society for Gastrointestinal Endoscopy, 2024 -- Guideline on the role of therapeutic EUS in biliary tract disorders
  2. Endoscopic Ultrasound-Assisted Gastrojejunostomy for Managing Gastric Outlet Obstruction: A Multi-Center Study from the UK, Surgical Endoscopy, 2022
  3. Minimally Invasive Approaches to Treating Benign Gallbladder Disorders, The New Gastroenterologist, 2025
  4. Comparative Efficacy of Endoscopic Negative Pressure Therapy versus Stent Placement for Managing Staple Line Leaks Following Sleeve Gastrectomy, Obesity Surgery, 2021
  5. Endoluminal Vacuum Therapy Using VACStent for Managing Anastomotic Leaks in Colorectal Surgery: A Pilot Investigation to Avoid Stoma Formation
  6. ASGE | American Society for Gastrointestinal Endoscopy guideline on the role of therapeutic EUS in the management of biliary tract disorders: summary and recommendations
  7. Endoscopic ultrasound-guided biliary drainage versus endoscopic retrograde cholangiopancreatography biliary drainage in the palliative management of malignant distal biliary obstruction: an updated systematic review and meta-analysis of randomized controlled trials - PubMed
  8. Usefulness of a dedicated laser-cut metal stent with an anchoring hook and thin delivery system for EUS-guided hepaticogastrostomy in malignant biliary obstruction: a prospective multicenter trial (with video) - PubMed

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