Evaluation of nosocomial infections after congenital heart surgery in children: A comprehensive analysis including the systemic immune-inflammation index (SII) - Report - MDSpire
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Evaluation of nosocomial infections after congenital heart surgery in children: A comprehensive analysis including the systemic immune-inflammation index (SII)
Clinical Report: Assessment of Hospital-Acquired Infections in Pediatric Patients Post-Congenital Heart Surgery
Overview
This study identifies independent risk factors for nosocomial infections (NIs) in pediatric patients following congenital heart surgery and evaluates the predictive utility of the Systemic Immune-Inflammation Index (SII). Key findings indicate that younger age, prolonged mechanical ventilation, and postoperative complications significantly increase the risk of NIs.
Background
Hospital-acquired infections (HAIs) are a major concern in pediatric cardiac surgery, contributing to increased morbidity and mortality. Understanding the risk factors associated with NIs can help improve patient outcomes and inform infection control strategies. The Systemic Immune-Inflammation Index (SII) has been proposed as a potential predictive tool for infection risk in this vulnerable population.
NIs occurred in 22.0% of pediatric patients post-cardiac surgery.
Sepsis (69.6%) and pneumonia (30.4%) were the most common types of NIs.
Gram-negative bacteria were identified in 58.4% of NIs.
Postoperative complications were the strongest independent predictor of NIs.
Postoperative SII did not retain strong predictive value for NIs in multivariate analysis.
Younger age and prolonged mechanical ventilation significantly increased NI risk.
Clinical Implications
Healthcare providers should focus on identifying high-risk patients, particularly younger children and those requiring prolonged mechanical ventilation, to implement targeted infection prevention strategies. The findings highlight the importance of managing postoperative complications to reduce the incidence of NIs.
Conclusion
The study underscores the critical need for stringent infection control measures in pediatric cardiac surgery. While SII correlates with infection status, it may not serve as a reliable independent predictor in this context.
