Liver stiffness measured by transient elastography is associated with hepatic Fibrosis in children with portal vein thrombosis: a retrospective cross-sectional study - Report - MDSpire

Liver stiffness measured by transient elastography is associated with hepatic Fibrosis in children with portal vein thrombosis: a retrospective cross-sectional study

  • By

  • Marwah Imad Shihab

  • Noor Mohammed Abdullah

  • Abdulnaser Karem Mhmeed

  • Enas Osama Hassan Omer

  • Aya Ahmed Shimal

  • Ahmed Osama Hassan Omer

  • Ahmed Dheyaa Al-Obaidi

  • June 5, 2026

  • 0 min

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Clinical Report: Assessment of Liver Stiffness in Pediatric Portal Vein Thrombosis

Overview

This study evaluates the correlation between liver stiffness measurement (LSM) via transient elastography and hepatic fibrosis in pediatric patients with portal vein thrombosis (PVT). Findings indicate that LSM is a strong predictor of fibrosis stage, outperforming traditional indicators such as platelet count.

Background

Extrahepatic portal vein obstruction (EHPVO) is a significant cause of portal hypertension in children, often resulting from portal vein thrombosis (PVT). Accurate assessment of hepatic fibrosis is crucial for determining disease severity and guiding management. Non-invasive techniques like transient elastography (TE) provide safer alternatives to liver biopsy, particularly in pediatric populations.

Data Highlights

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Key Findings

{'add': 'Include statistical values or confidence intervals for claims made.'}

Clinical Implications

{'expand': 'Discuss integration of LSM into clinical practice.'}

Conclusion

{'reiterate': 'Emphasize the impact of TE on patient outcomes with examples.'}

Related Resources & Content

  1. Frontiers, Source, 2026 -- Liver Stiffness Measured by Transient Elastography is Associated with Hepatic Fibrosis in Children with Portal Vein Thrombosis
  2. The New Gastroenterologist, Source, 2025 -- Assessment of Liver Stiffness as a Predictor of Long-Term Prognosis in Children with Biliary Atresia
  3. European Radiology, Source, 2025 -- Validation of T1ρ Mapping Techniques for Evaluating Hepatic Fibrosis in Individuals with Chronic Liver Conditions
  4. EASL Clinical Practice Guidelines on vascular diseases of the liver, Source, 2025
  5. WFUMB GUIDELINES ON MULTIPARAMETRIC ULTRASOUND FOR DIFFUSE LIVER DISEASE, Source, 2025
  6. Obesity Surgery — Frequency of Increased Liver Stiffness in Prospective Bariatric Surgery Candidates in the United States
  7. Pediatric Cardiology — Assessment of Heart Function in Pediatric Patients Undergoing Liver Transplantation
  8. EASL Clinical Practice Guidelines on vascular diseases of the liver - ScienceDirect
  9. WFUMB GUIDELINES ON MULTIPARAMETRIC ULTRASOUND FOR DIFFUSE LIVER DISEASE: DEVELOPMENT AND RECOMMENDATIONS - ScienceDirect
  10. Frontiers | Liver Stiffness Measured by Transient Elastography is Associated with Hepatic Fibrosis in Children with Portal Vein Thrombosis: A Retrospective Cross-Sectional Study

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