Trends in the Epidemiology of Retinopathy of Prematurity in Northwest China: A Ten-Year Retrospective Study from a Single Center (2015–2024)
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By
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Jing Yang
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Le Zhang
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July 21, 2026
Clinical Report: Trends in the Epidemiology of Retinopathy of Prematurity in Northwest China
Overview
This study analyzes the incidence trends of retinopathy of prematurity (ROP) over a decade at a single center in Northwest China.
Background
Retinopathy of prematurity is a significant cause of childhood blindness, affecting premature infants globally. The incidence of ROP varies widely, and despite advancements in neonatal care, the disease remains prevalent. Effective screening is crucial for early detection and treatment.
Data Highlights
| Gestational Age (GA) | ROP Incidence Rate | Treatment-Requiring Rate |
|---|---|---|
| GA <28 weeks | 72.37% | 33.00% |
| GA 28–<32 weeks | 23.04% | 1.39% |
| GA ≥32 weeks | 6.17% | 0.12% |
Key Findings
- The overall ROP incidence rate was 14.18% across the study period.
- A total of 12,640 infants underwent 31,605 screenings, averaging 2.44 screenings per infant.
- ROP burden decreased significantly with increasing gestational age.
- Annual screening volume and treatment demand showed fluctuating upward trends over the decade.
Clinical Implications
The findings suggest that infants with GA <28 weeks require intensive screening, while those with GA ≥32 weeks may have reduced screening frequency. This approach could optimize resource allocation while ensuring high-risk infants are adequately monitored.
Conclusion
The study underscores the ongoing challenges in ROP screening and the need for tailored strategies to improve outcomes for premature infants.
Related Resources & Content
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- Recurrence of Retinopathy of Prematurity Following Anti-vascular Endothelial Growth Factor (Anti-VEGF) Therapy: A Systematic Review and Meta-Analysis - PubMed
- Time Course of Retinopathy of Prematurity Regression and Reactivation After Treatment with Ranibizumab or Laser in the RAINBOW Trial - ScienceDirect
- 早产儿视网膜病预防管理专家共识(2024) 中华医学会围产医学分会
Based on findings from:
Epidemiology of retinopathy of prematurity (ROP) in Northwest China: a decade-long retrospective single-center analysis (2015–2024)
Jing Yang, Le Zhang. Frontiers In Pediatrics, 2026.
https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1874909/full
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