Adiposity and domain-specific menopausal symptom severity in midlife women: a cross-sectional clinical study in eastern china - Report - MDSpire

Adiposity and domain-specific menopausal symptom severity in midlife women: a cross-sectional clinical study in eastern china

  • By

  • Miao Deng

  • Hongyan Zhang

  • Zhifen Zhang

  • Nan Chen

  • May 22, 2026

  • 0 min

Share

Clinical Report: The Relationship Between Body Weight and Menopausal Symptoms

Overview

This study investigates the association between body mass index (BMI) and the prevalence and severity of menopausal symptoms in peri- and postmenopausal women in Eastern China. While overall symptom prevalence did not differ significantly across BMI categories, higher BMI was associated with increased severity of specific symptoms such as vasomotor symptoms and sexual dysfunction.

Background

Menopause significantly impacts the health and quality of life of women, with a high prevalence of symptoms such as vasomotor disturbances and sexual dysfunction. Understanding the relationship between body weight and menopausal symptoms is crucial.

Data Highlights

No numerical data available in the source material.

Key Findings

  • Vasomotor symptoms were reported by 76.6% of participants, with high frequencies of sexual dysfunction (72.4%), fatigue (72.0%), insomnia (71.8%), and mood swings (66.3%).
  • Overall prevalence of menopausal symptoms did not significantly differ across BMI categories.
  • Significant positive correlations were found between BMI and the severity of vasomotor symptoms, mood swings, sexual dysfunction, and urinary symptoms.
  • Women with obesity had significantly higher scores for vasomotor, sexual, and urinary symptoms compared to women of normal weight.
  • These associations remained statistically significant but modest after adjusting for waist-to-hip ratio.

Clinical Implications

Clinicians should consider the potential impact of BMI on the severity of menopausal symptoms when assessing and managing women in midlife. Tailored interventions may be necessary to address the specific symptom burdens associated with different BMI categories.

Conclusion

The study highlights a modest association between BMI and the severity of certain menopausal symptoms. Further research is needed to explore these relationships in greater depth.

Related Resources & Content

  1. American Journal of Epidemiology, 2023 -- Impact of Weight Fluctuations from Adolescence to Midlife on the Timing of Natural Menopause
  2. JAMA Network Open, 2023 -- Optimal Dietary Patterns for Lower Weight Gain and Risk of Obesity Surrounding Menopause
  3. The Journal of Clinical Endocrinology & Metabolism, 2023 -- Insulin Levels Early in Perimenopause Inform Vasomotor Symptom Incidence Across the Menopausal Transition
  4. Frontiers in Endocrinology, 2026 -- Adipose–muscle crosstalk during the menopausal transition: mechanistic links to sarcopenic obesity in midlife women
  5. Menopause - NCBI Bookshelf, 2024 -- Current guidance on menopause management
  6. Factors Associated With Menopause Symptoms: A Systematic Review and Meta-Analysis - PubMed, 2023
  7. MENO_230215, 2023 -- Nonhormone therapy position statement
  8. Menopause - NCBI Bookshelf
  9. Factors Associated With Menopause Symptoms: A Systematic Review and Meta-Analysis - PubMed
  10. MENO_230215 573..590

Original Source(s)

Related Content