Construction and validation of a tracheostomy prediction model in mechanically ventilated stroke patients and the impact of early versus late tracheostomy on clinical outcomes: an IPTW-based analysis - Report - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Development and assessment of a predictive model for tracheostomy in stroke patients on mechanical ventilation, along with the effects of early versus delayed tracheostomy on clinical outcomes: an IPTW-based evaluation

  • By

  • Miaoxinhui Shao

  • Wenjie Pan

  • Yanxin Liu

  • Hui Wang

  • Xiaoxia Duan

  • July 21, 2026

Share

Clinical Report: Predictive Model for Tracheostomy in Stroke Patients

Overview

This study developed a predictive model for tracheostomy in mechanically ventilated stroke patients and assessed the impact of early versus delayed tracheostomy on clinical outcomes. The model demonstrated good performance in predicting tracheostomy risk.

Background

Stroke is a leading cause of death and disability globally, with a significant number of patients requiring prolonged mechanical ventilation. Tracheostomy is a common intervention in these cases, associated with both benefits and risks. Understanding the optimal timing for tracheostomy is crucial for improving patient outcomes.

Data Highlights

Predictorp-value
Midline shift< 0.05
Hypoalbuminemia< 0.05
Admission GCS score< 0.05
CRP< 0.05
PNI< 0.05

Key Findings

  • Independent predictors for tracheostomy included midline shift, hypoalbuminemia, admission GCS score, CRP, and PNI.
  • The predictive model achieved an AUC of 0.855 in the training set and 0.849 in the validation set.
  • No significant effect was observed on post-tracheostomy ventilation duration, antibiotic use duration, total hospital stay, or hospitalization costs.

Clinical Implications

The developed nomogram allows for individualized risk assessment for tracheostomy in stroke patients on mechanical ventilation.

Conclusion

The predictive model for tracheostomy in stroke patients shows potential for clinical application. Further validation is warranted.

Related Resources & Content

  1. Frontiers in Neurology, 2026 -- Establishment and evaluation of a predictive scoring system for successful decannulation of tracheostomy in neurosurgery patients
  2. Intensive Care Medicine, 2008 -- Evaluating the Advantages of Early Tracheotomy: Are They Overstated or Insufficiently Supported?
  3. Intensive Care Medicine, 2024 -- Optimal Clinical Model for Predicting Extubation Failure: A Post Hoc Analysis of Diagnostic Accuracy
  4. Emergency Surgical Patients and Airway Management: Evaluating the Role of Backup Surgical Procedures
  5. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke - Professional Heart Daily | American Heart Association
  6. Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial - PMC
  7. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke - Professional Heart Daily | American Heart Association
  8. Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial - PMC

Original Source(s)

Construction and validation of a tracheostomy prediction model in mechanically ventilated stroke patients and the impact of early versus late tracheostomy on clinical outcomes: an IPTW-based analysis

  • by Miaoxinhui Shao, Wenjie Pan, Yanxin Liu, Hui Wang, Xiaoxia Duan

  • July 21, 2026

Related Content

FDA Approves New Iohexol Vials

The approval includes additional 300 mg iodine/mL and 350 mg iodine/mL vial presentations.

Treatment first, transport second: rethinking stroke management with mobile stroke units—A systematic review and meta-analysis of controlled trials

Baptist Health Brain & Spine Care to Host 14th Annual Miami Neuroscience Symposium Nov. 4-6, Bringing Leading Experts Together to Explore Advances in Brain and Spine Care

Baptist Health will bring together leading physicians, researchers and healthcare professionals from South Florida and across the country for the 14th Annual Baptist Health Miami Neuroscience Symposium, taking place Nov. 4-6, 2026, at Hilton Miami Dadeland and virtually via Zoom.

  • by

  • August 21, 2026

  • 5 min