Lymphoepithelioma-like carcinoma of the bladder: a case report - Report - MDSpire

Lymphoepithelioma-like carcinoma of the bladder: a case report

  • By

  • Ying Yu

  • Lei Zhang

  • July 8, 2026

  • 0 min

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Clinical Report: Case Study of Lymphoepithelioma-like Carcinoma in the Bladder

Background

Lymphoepithelioma-like carcinoma of the bladder is a rare subtype of urothelial carcinoma, accounting for less than 1.3% of malignant bladder tumors. Its rarity complicates the establishment of standardized treatment protocols and prognostic factors. Understanding this subtype is crucial.

Data Highlights

No numerical or trial data available in the article, which limits the ability to draw broader conclusions.

Key Findings

  • LELCB accounts for approximately 1% of all malignant bladder tumors.
  • The case presented involved an 86-year-old female with painless gross hematuria.
  • Histopathological examination revealed characteristic lymphoepithelioma-like morphology with a dense lymphoid stroma.
  • The patient experienced a recurrence of LELCB 11 months after initial treatment.
  • Adjuvant chemotherapy with epirubicin hydrochloride was administered post-surgery.
  • LELCB is not associated with EBV infection, unlike similar tumors in other sites.

Clinical Implications

Clinicians should be aware of the potential for recurrence in patients with LELCB.

Conclusion

This case adds to the limited literature on LELCB.

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