Quality of Life in Cardiac Arrest Recovery - Report - MDSpire

Quality of Life in Cardiac Arrest Recovery

  • By

  • Kathryn Wighton

  • February 19, 2026

  • 4 min

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Quality of Life in Cardiac Arrest Recovery

Overview

A recent observational study links health-related quality of life (HRQOL) post-cardiac arrest to long-term survival outcomes. Poor HRQOL scores at 3 to 6 months post-event were associated with increased mortality risk, particularly in survivors of in-hospital cardiac arrest.

Background

Understanding the long-term outcomes of cardiac arrest survivors is crucial for improving patient care and rehabilitation strategies. Health-related quality of life (HRQOL) serves as an important indicator of recovery and can inform follow-up care. This study highlights the need for systematic HRQOL assessments in post-cardiac arrest management.

Data Highlights

PopulationHRQOL ScoreMortality Risk
IHCA Survivors11-252x higher risk
OHCA SurvivorsContinuous variable analysis indicated increasing risk with poorer HRQOL.Increasing risk with poorer HRQOL

Key Findings

  • Among IHCA survivors, those with HRQOL scores of 11-25 had over twice the mortality risk compared to those with scores of 5.
  • Intermediate HRQOL scores (6-10) did not show significant mortality differences.
  • For OHCA survivors, categorical HRQOL scores were not significantly associated with mortality, but continuous measures indicated increased risk with poorer health.
  • Depressive symptoms negatively impacted long-term survival in IHCA survivors, while anxiety symptoms did not.
  • Nearly 50% of eligible IHCA survivors and over 60% of OHCA survivors had missing HRQOL data, raising concerns about selection bias and generalizability.
  • The study utilized the EuroQoL 5-dimension 5-level tool for HRQOL assessment, indicating its relevance in post-cardiac arrest care.

Clinical Implications

Healthcare providers should prioritize systematic HRQOL assessments in cardiac arrest survivors to identify those at higher risk for mortality. This information can guide follow-up care and support interventions aimed at improving quality of life during recovery.

Conclusion

The association between HRQOL and long-term survival underscores the importance of integrating quality of life measures into post-cardiac arrest care protocols. Enhanced focus on HRQOL can lead to better patient outcomes and tailored rehabilitation strategies, while addressing concerns about selection bias due to missing data.

References

  1. Dillenbeck E., JAMA Network Open, 2023 -- Quality of Life in Cardiac Arrest Recovery
  2. Critical Care (Springer) — Impact of VA-ECMO on Long-Term Quality of Life in Patients with Post-Cardiotomy Cardiogenic Shock: Insights from a Prospective Study
  3. European Journal of Preventive Cardiology — Quality of life in heart failure. The heart of the matter. A scientific statement of the Heart Failure Association and the European Association of Preventive Cardiology of the European Society of Cardiology
  4. Critical Care (Springer) — One-year trajectory of psychological symptoms in families of out-of-hospital cardiac arrest patients
  5. Clinical Research in Cardiology — Clinical Features, Etiologies, and Outcome Predictors in Patients Experiencing In-Hospital Cardiac Arrest: Findings from the SURVIVE-ARREST Study
  6. Post-Cardiac Arrest Care | American Heart Association
  7. Long-Term Outcomes and Recovery Trajectories in Out-of-Hospital Cardiac Arrest: A 2-Year Follow-Up of the Randomized Clinical TTM2 Trial | Cardiology | JAMA Neurology | JAMA Network

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