Organizational models for acute gastrointestinal bleeding: a systematic review of hospital networks, multidisciplinary care and bloodless programs (2015–2025) - Report - MDSpire

Organizational models for acute gastrointestinal bleeding: a systematic review of hospital networks, multidisciplinary care and bloodless programs (2015–2025)

  • By

  • Sungat Otegen

  • Lyudmila S. Yermukhanova

  • Abylai Baimakhanov

  • Negar Ashuri

  • Aruzhan Otegenova Muratkyzy

  • Aidyn Armanuly Zhylgeldy

  • Murat Jakanov

  • Gulbanu Arynova

  • Alireza Afshar

  • July 2, 2026

  • 0 min

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Clinical Report: Models of Care for Acute Gastrointestinal Hemorrhage

Overview

This systematic review evaluates organizational models for managing acute gastrointestinal bleeding. Evidence remains limited, with no significant mortality differences noted between networked and non-networked hospitals.

Background

Acute gastrointestinal bleeding is a prevalent cause of hospital admissions, significantly impacting healthcare costs and patient outcomes. Despite advancements in treatment, mortality rates remain concerning.

Data Highlights

Three studies met the inclusion criteria, revealing varied outcomes based on care models.

Key Findings

  • Hub and spoke network hospitals showed no difference in risk-adjusted mortality compared to non-network hospitals.
  • Multidisciplinary team programs for cirrhotic variceal bleeding reported lower mortality and reduced readmissions.
  • Bloodless medicine initiatives achieved low mortality rates despite low hemoglobin levels.
  • Quality of life and patient-reported outcomes were rarely reported across studies.
  • All studies were assessed to have serious risk of bias and limited generalizability.

Clinical Implications

Continuous evaluation of organizational models is necessary to enhance patient outcomes and care efficiency.

Conclusion

The review indicates that the overall evidence on organizational strategies for acute gastrointestinal bleeding remains sparse.

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- Predictive model for in-hospital acute cerebral infarction in patients with acute gastrointestinal bleeding
  2. Intensive Care Medicine, 2021 -- Guidelines for Blood Transfusion Approaches in Critically Ill Adults with Bleeding
  3. Frontiers in Pediatrics, 2026 -- Optimizing hemostasis to prevent bleeding and reduce transfusion requirements in neonatal and infant cardiac surgery
  4. The New Gastroenterologist, 2025 -- Understanding Lower Gastrointestinal Bleeding: Insights from Two Experts
  5. Endoscopic diagnosis and management of peptic ulcer bleeding: ESGE Guideline - Update 2026
  6. Canadian Association of Gastroenterology Clinical Practice Guideline for the Endoscopic Management of Nonvariceal Nonpeptic Ulcer Upper Gastrointestinal Bleeding, 2025
  7. Time to endoscopy and its effect on outcomes in acute nonvariceal and variceal upper gastrointestinal bleeding, 2026
  8. JAG Accreditation, 2025 -- Revised standards for public consultation
  9. NHS England, Gastro-intestinal endoscopy networks: A development framework
  10. Patient Blood Management: a systematic review of current international guidelines
  11. Risk factors for rebleeding in acute lower gastrointestinal bleeding: a systematic review and meta-analysis
  12. Frontiers | Organizational Models for Acute Gastrointestinal Bleeding: A Systematic Review of Hospital Networks, Multidisciplinary Care and Bloodless Programs (2015–2025)
  13. Endoscopic diagnosis and management of peptic ulcer bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2026 - PubMed
  14. Canadian Association of Gastroenterology Clinical Practice Guideline for the Endoscopic Management of Nonvariceal Nonpeptic Ulcer Upper Gastrointestinal Bleeding
  15. Time to endoscopy and its effect on outcomes in acute nonvariceal and variceal upper gastrointestinal bleeding - PubMed
  16. JAG Accreditation
  17. NHS England » Gastro-intestinal endoscopy networks: A development framework
  18. Patient Blood Management: a systematic review of current international guidelines - PubMed
  19. Risk factors for rebleeding in acute lower gastrointestinal bleeding: a systematic review and meta-analysis - PubMed
  20. Frontiers | Organizational Models for Acute Gastrointestinal Bleeding: A Systematic Review of Hospital Networks, Multidisciplinary Care and Bloodless Programs (2015–2025)

Original Source(s)

Organizational models for acute gastrointestinal bleeding: a systematic review of hospital networks, multidisciplinary care and bloodless programs (2015–2025)

  • by Sungat Otegen, Lyudmila S. Yermukhanova, Abylai Baimakhanov, Negar Ashuri, Aruzhan Otegenova Muratkyzy, Aidyn Armanuly Zhylgeldy, Murat Jakanov, Gulbanu Arynova, Alireza Afshar

  • July 2, 2026

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