Development of a semi–real-time electrocardiogram monitoring system integrating artificial intelligence and wearable devices for atrial fibrillation screening - Report - MDSpire

Development of a semi–real-time electrocardiogram monitoring system integrating artificial intelligence and wearable devices for atrial fibrillation screening

  • By

  • Si Van Nguyen

  • Minh Khac Ho

  • Dat Vu Nguyen

  • Canh Quang Nguyen

  • An Le Pham

  • Hung Thanh Quach

  • June 8, 2026

  • 0 min

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Clinical Report: Creation of a Semi-Real-Time ECG Monitoring System Utilizing AI

Overview

This study developed a deep learning-based AI model for detecting atrial fibrillation (AF) using 24-hour Holter ECG data. It also assessed the feasibility of a semi-real-time monitoring framework integrating AI analysis with wearable ECG devices for high-risk populations.

Background

Atrial fibrillation is a common cardiac arrhythmia linked to a higher risk of thromboembolic events, particularly ischemic stroke. Timely detection and management of AF can significantly reduce stroke risk, making effective screening methods essential. Traditional ECG monitoring methods often miss paroxysmal AF episodes, highlighting the need for improved diagnostic technologies.

Data Highlights

DatasetRecordings
Training Dataset1,089
Evaluation Dataset400

Key Findings

  • A total of 1,489 Holter ECG recordings were analyzed, with 135 excluded for incomplete demographic data.
  • The AI model demonstrated improved accuracy in detecting AF compared to traditional methods.
  • Inter-rater agreement for AF episode annotation was high (κ = 0.92) between two cardiologists.
  • The study implemented a semi-real-time monitoring framework integrating AI with wearable ECG devices.
  • AI analysis can enhance AF detection in high-risk populations.

Clinical Implications

The integration of AI in ECG monitoring may enhance the detection of atrial fibrillation, particularly in patients at high risk for stroke. Clinicians should consider utilizing AI-enabled tools for more effective screening and management of AF.

Conclusion

The study highlights the potential of AI-driven ECG monitoring systems to improve atrial fibrillation detection and management. Further research is needed to validate these findings in broader clinical settings.

Related Resources & Content

  1. Clinical Research in Cardiology, 2022 -- Utilizing Machine Learning for Identifying and Managing Atrial Fibrillation
  2. npj Digital Medicine, 2025 -- Artificial intelligence-enabled analysis of handheld single-lead electrocardiograms to predict incident atrial fibrillation: an analysis of the VITAL-AF randomized trial
  3. npj Digital Medicine, 2026 -- Electrocardiographic Age from Wearable Devices and Its Link to Atrial Fibrillation
  4. Clinical Research in Cardiology, 2021 -- A Systematic Review of Mobile Health Technologies for the Detection and Management of Atrial Fibrillation
  5. 2024 ESC AF Guidelines
  6. JACC, 2025 -- Diagnostic Accuracy of Smartwatches and Wearable Devices Using Photoplethysmography and Electrocardiography for Atrial Fibrillation Detection: A Systematic Review and Meta-Analysis
  7. New England Journal of Medicine -- Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation
  8. https://www.escardio.org/static-file/Escardio/Guidelines/Products/Essential%20Messages/2024%20EM/Essential%20Messages_2024%20AFib.pdf
  9. DIAGNOSTIC ACCURACY OF SMARTWATCHES AND WEARABLE DEVICES USING PHOTOPLETHYSMOGRAPHY AND ELECTROCARDIOGRAPHY FOR ATRIAL FIBRILLATION DETECTION: A SYSTEMATIC REVIEW AND META-ANALYSIS | JACC
  10. Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation | New England Journal of Medicine

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