The relationship between cardiometabolic index and the coexistence of hypertension and diabetes in individuals aged 45 and above: insights from two national datasets - Report - MDSpire

The relationship between cardiometabolic index and the coexistence of hypertension and diabetes in individuals aged 45 and above: insights from two national datasets

  • By

  • Dong Yang

  • Jialiang Huang

  • Lincheng Duan

  • Zeping Chen

  • Yue Feng

  • January 28, 2026

  • 0 min

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Clinical Report: CMI and Hypertension-Diabetes Coexistence in Adults 45+

Overview

This study investigates the relationship between the cardiometabolic index (CMI) and the coexistence of hypertension and diabetes in individuals aged 45 and above, utilizing data from national datasets in China and the United States. Findings suggest that CMI may serve as a valuable indicator for identifying populations at risk for hypertension-diabetes comorbidity.

Background

Hypertension and diabetes are prevalent conditions that significantly contribute to cardiovascular and renal complications, particularly in midlife and older adults. The rising prevalence of these conditions poses a substantial economic burden on healthcare systems. Understanding the interplay between these diseases and identifying effective screening tools, such as the CMI, is crucial for public health strategies aimed at reducing associated risks.

Data Highlights

No specific numerical data or trial data presented in the article.

Key Findings

  • The prevalence of hypertension among adults aged 18 and older in the U.S. is 47.7%.
  • Approximately 38.5 million individuals aged 20–79 in the U.S. have diabetes, with projections reaching 43 million by 2050.
  • CMI is a novel metric that reflects adiposity and lipid profiles, potentially aiding in the identification of high-risk populations.
  • Prior research has not established the association between CMI and hypertension-diabetes comorbidity specifically in middle-aged and older populations.
  • This study utilizes data from NHANES and CHARLS to explore the CMI's relevance in both American and Chinese populations.

Clinical Implications

Healthcare professionals should consider the cardiometabolic index as a potential screening tool for identifying individuals at risk for hypertension and diabetes comorbidity. Early identification may facilitate targeted interventions to mitigate cardiovascular and renal complications associated with these conditions.

Conclusion

The study highlights the importance of the cardiometabolic index in understanding the coexistence of hypertension and diabetes among older adults, suggesting its utility in public health initiatives aimed at reducing disease burden.

References

  1. American Journal of Epidemiology, 2023 -- Combined Impact of Dietary Habits and Physical Activity on the Development of Type 2 Diabetes and Hypertension: Insights from 144,288 Participants in the UK Biobank
  2. European Journal of Preventive Cardiology, 2023 -- Variations in the Relationship Between Modifiable Lifestyle Risk Factors and New-Onset Cardiovascular Disease in Diabetic versus Non-Diabetic Individuals
  3. European Journal of Preventive Cardiology, 2023 -- Addressing the Intersection of Diabetes and Cardiovascular Disease Prevention: Tackling Two Major Health Challenges
  4. European Journal of Preventive Cardiology, 2023 -- Cardiovascular Risk in Diabetes: An Ongoing Evolution
  5. CDC Data Briefs, 2024 -- Products - Data Briefs - Number 511 -October 2024
  6. Products - Data Briefs - Number 511 -October 2024
  7. . RxFiles.ca Trial Summary Sept 2010 A
  8. Exploring the nonlinear association between cardiometabolic index and hypertension in U.S. Adults: an NHANES-based study - PMC

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