Correction: Birth weight, ototoxic medication, and surgical history predict individual hearing loss risks: a systematic review and meta-analysis - Report - MDSpire
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Correction: Factors Influencing Individual Hearing Loss Risk: A Systematic Review and Meta-Analysis of Birth Weight, Ototoxic Medications, and Surgical Background

  • By

  • Hanwen Luo

  • Jianghua He

  • Dapeng Chen

  • Xiaoming Xu

  • Jing Zhao

  • Xiaoyan Yang

  • Jing Shi

  • August 12, 2026

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Correction: Factors Influencing Individual Hearing Loss Risk

Overview

This correction addresses significant associations with hearing loss in NICU neonates linked to factors such as ototoxic drug exposure, craniofacial anomalies, and surgical history. Low birth weight did not show a significant correlation with hearing loss.

Background

Understanding the risk factors for hearing loss in neonates is crucial for early detection and intervention strategies. This systematic review and meta-analysis provide insights into various factors influencing hearing loss risk in neonatal intensive care unit (NICU) patients.

Data Highlights

No significant risk of hearing loss was found in very low birth weight neonates (<1,500 g) with an odds ratio of 3.05 (95% CI [0.57, 16.38], P = 0.19). Additionally, postnatal hypoxia and sepsis showed no significant association with hearing loss.

Key Findings

  • Significant associations with hearing loss in NICU neonates were found for ototoxic drugs, craniofacial anomalies, family history of hearing loss, surgical ligation of PDA, and TORCH infections (all P ≤ 0.05).
  • No significant correlation was observed between low birth weight and hearing loss in neonates.
  • Postnatal hypoxia/severe birth asphyxia did not show a significant association with hearing loss (OR = 0.81, P = 0.07).
  • Sepsis presented no significant association with hearing loss (OR = 1.03, P = 0.85).
  • Hyperbilirubinemia and mechanical ventilation were noted as risk factors for hearing loss.

Clinical Implications

The identified risk factors for hearing loss in NICU patients are ototoxic drug exposure, craniofacial anomalies, family history of hearing loss, surgical ligation of PDA, and TORCH infections.

Conclusion

This correction emphasizes specific risk factors in predicting hearing loss in neonates.

Related Resources & Content

  1. Luo H, He J, Chen D, Xu X, Zhao J, Yang X, Shi J, Front Pediatr, 2026 -- Factors Influencing Individual Hearing Loss Risk: A Systematic Review and Meta-Analysis
  2. Frontiers in Pediatrics — Prognostic Factors for Pediatric Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-Analysis
  3. Frontiers in Pediatrics — Systems perspectives on pediatric otitis media: environmental exposures, genetic susceptibility, and biomarker-guided interventions
  4. MDSpire News — Race, Sex Gaps Reshape Hearing Loss Landscape
  5. MDSpire News — Hearing Loss Burden Rises in Working-Age Adults
  6. Screening for Hearing Loss | Hearing Loss in Children | CDC
  7. Anhydrous sodium thiosulfate for preventing hearing loss caused by cisplatin chemotherapy
  8. Birth weight, ototoxic medication, and surgical history predict individual hearing loss risks: a systematic review and meta-analysis - PMC

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