Dietary background, serum polyunsaturated fatty acid profiles, and 1-year outcomes after large-artery atherosclerotic stroke: a multicenter cohort study - Report - MDSpire
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Dietary background, serum polyunsaturated fatty acid profiles, and 1-year outcomes after large-artery atherosclerotic stroke: a multicenter cohort study
Clinical Report: Influence of Long-Term Dietary Habits on Stroke Outcomes
Overview
This study investigates the association between long-term dietary habits and post-stroke outcomes in patients with large-artery atherosclerotic cerebral infarction (LAA-CI). It finds differences in neurological and functional recovery between a high-fish/seafood diet and a mixed/omnivorous diet, with serum polyunsaturated fatty acid (PUFA) profiles being assessed.
Background
Stroke is a leading cause of long-term disability, particularly large-artery atherosclerotic cerebral infarction (LAA-CI) in Asian populations. Understanding modifiable factors, such as dietary habits, is important for post-stroke recovery. This study investigates the impact of dietary patterns and serum PUFA levels on recovery outcomes in stroke patients.
Data Highlights
Dietary Group
mRS Score
Poor Functional Outcome
Post-Stroke Depression
Cognitive Impairment
High-Fish/Seafood
Lower
Lower Incidence
Lower Rates
Lower Rates
Mixed/Omnivorous
Higher
Higher Incidence
Higher Rates
Higher Rates
Key Findings
Patients with a high-fish/seafood diet had lower mRS scores at 1-year follow-up.
Lower incidence of poor functional outcomes was observed in the high-fish/seafood group.
Higher ω-3 levels and lower ω-6/ω-3 ratios were found in the high-fish/seafood group.
Higher ω-6/ω-3 ratios were associated with increased risks of poor functional outcomes and post-stroke depression.
Neurological improvement was noted in the high-fish/seafood dietary group.
Clinical Implications
The findings indicate that dietary habits, particularly the consumption of fish and seafood, may influence recovery outcomes in stroke patients.
Conclusion
Long-term dietary habits impact post-stroke recovery, with the ω-6/ω-3 ratio identified as a potential metabolic marker for outcomes.