Understanding Racial Variations in Secondary Treatment and Survival in Localized Prostate Cancer - Report - MDSpire

Exploring Racial Disparities in Follow-Up Treatment and Survival Rates for Localized Prostate Cancer

  • By

  • Martin W. Schoen

  • June M. McKoy

  • Charles L. Bennett

  • July 21, 2026

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Clinical Report: Exploring Racial Disparities in Follow-Up Treatment and Survival Rates for Localized Prostate Cancer

Overview

This study investigates racial disparities in secondary treatment and survival rates for localized prostate cancer, focusing on the differences in therapy receipt between Black and White men.

Background

Racial disparities in prostate cancer treatment and outcomes have been a persistent concern, particularly regarding the differences in therapy receipt between Black and White men. Previous studies have shown that Black men are less likely to receive definitive therapy. Understanding these disparities is crucial for improving equity in prostate cancer care.

Data Highlights

The study utilized the Medicare-SEER database, analyzing over 80,000 patients diagnosed between 2004 and 2017. Key findings include:

Key Findings

  • Secondary treatment receipt after primary definitive treatment was similar across races.
  • Black men exhibited features of higher-risk disease compared to White men.
  • Black men who did not receive secondary therapy had a higher risk of prostate cancer-specific mortality.
  • Black men were less likely to receive systemic therapy as a secondary treatment.
  • Disparities in care may be attributed to variations in the receipt of secondary treatments among Black patients.

Clinical Implications

Healthcare providers should be aware of the disparities in secondary treatment receipt among Black men with prostate cancer.

Conclusion

Further research into the factors contributing to racial disparities in prostate cancer treatment and outcomes is needed.

Related Resources & Content

  1. Acolin et al, JAMA Network Open, 2023 -- Racial Differences in Secondary Treatment Pathways and Survival in Localized Prostate Cancer
  2. Rude et al, ADA News, 2021 -- Study Investigates Influence of Race on Receipt of Care for Prostate Cancer
  3. Shulman et al, The ASCO Post, 2024 -- Disparities in Treatment Outcomes Among Non-Hispanic Black Patients With Locally Advanced Rectal Cancer
  4. Survival Benefits of External Beam Radiotherapy in Asian Patients with Metastatic Prostate Cancer Compared to Other Racial and Ethnic Groups
  5. NCCN Guidelines® Insights: Prostate Cancer, Version 5.2026
  6. Salvage radiotherapy with or without hormonal therapy for biochemical recurrence after radical prostatectomy: A systematic review and meta-analysis
  7. Disparities in guideline-concordant treatment receipt for localized prostate cancer (PCa): A SEER-based analysis. | Journal of Clinical Oncology

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