Perioperative Outcomes of Robot-Assisted versus Video-Assisted Thoracoscopic Surgery for Non-Small Cell Lung Cancer: A Meta-Analysis Focusing on Real-World Clinical Studies in the Past 10 Years - Report - MDSpire

Perioperative Outcomes of Robot-Assisted versus Video-Assisted Thoracoscopic Surgery for Non-Small Cell Lung Cancer: A Meta-Analysis Focusing on Real-World Clinical Studies in the Past 10 Years

  • By

  • Zhu, Jianfang

  • Meng, Xiaopeng

  • Hu, Liyong

  • April 27, 2026

  • 0 min

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Clinical Report: Comparative Analysis of RATS and VATS for NSCLC

Overview

This meta-analysis evaluates the perioperative outcomes of robot-assisted thoracoscopic surgery (RATS) versus video-assisted thoracoscopic surgery (VATS) for non-small cell lung cancer (NSCLC). Findings indicate that while both techniques yield comparable safety and short-term outcomes, RATS demonstrates a higher lymph node yield and shorter operative times in lobectomy cases.

Background

Non-small cell lung cancer (NSCLC) represents over 80% of lung cancer cases, making effective surgical intervention critical. Minimally invasive lobectomy is a standard treatment for early-stage NSCLC, yet the comparative efficacy of RATS and VATS remains debated. Understanding the differences in perioperative outcomes is essential for optimizing surgical approaches and improving patient care.

Data Highlights

Verify and adjust the data to reflect accurate statistical outcomes from the meta-analysis.

Key Findings

  • No significant differences in intraoperative blood loss, postoperative length of stay, or complication rates between RATS and VATS.
  • RATS was associated with a higher lymph node yield compared to VATS.
  • In the lobectomy subgroup, RATS demonstrated shorter operative times.
  • Study quality varied, with 7 high-quality and 2 moderate-quality studies included.
  • Funnel plots indicated no substantial publication bias.

Clinical Implications

Surgeons may consider RATS as a viable option for patients with NSCLC, particularly when lymph node retrieval is a priority. The comparable safety profiles of RATS and VATS suggest that patient selection can be guided by specific clinical goals and resource availability.

Conclusion

RATS and VATS provide similar perioperative outcomes for NSCLC, with RATS offering advantages in lymph node yield and operative time in lobectomy cases. These findings support the continued use of both techniques in clinical practice.

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  2. Advancements in Robotic Colonic Resection: A Five-Year Review of Progress, 2020
  3. A Comprehensive Systematic Review of Robot-Assisted Surgery for Thoracic and Visceral Applications, 2023
  4. Comparison of Robotic and Laparoscopic Techniques in Liver Surgery: Insights from a Six-Year Study of 600 Patients at a Single Institution, 2021
  5. Early and locally advanced non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up, 2023
  6. Robotic-assisted thoracic surgery versus video-assisted thoracic surgery for patients undergoing lung resection: a systematic review and meta-analysis of randomized controlled trials, 2023
  7. Early and locally advanced non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up - PubMed
  8. Robotic-assisted thoracic surgery versus video-assisted thoracic surgery for patients undergoing lung resection: a systematic review and meta-analysis of randomized controlled trials - PubMed

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