A combined therapeutic approach: extracorporeal shock wave therapy and botulinum toxin in multiple sclerosis-related spasticity - Report - MDSpire

A combined therapeutic approach: extracorporeal shock wave therapy and botulinum toxin in multiple sclerosis-related spasticity

  • By

  • Arianna Sartori

  • Anna Favero

  • Laura Mazzari

  • Giulia Mazzon

  • Alessio Bratina

  • Antonio Bosco

  • Marinella Tomaselli

  • Paolo Manganotti

  • June 16, 2026

  • 0 min

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Clinical Report: Integrative Treatment Strategy for Spasticity in MS

Overview

This study evaluates the efficacy of combining focal extracorporeal shock wave therapy (fESWT) with botulinum toxin injections (BTI) for treating spasticity in patients with multiple sclerosis (MS). Results indicate that this integrative approach provides both immediate and sustained clinical benefits.

Background

Spasticity is a prevalent and debilitating symptom in multiple sclerosis, affecting approximately 65% of patients. Traditional treatments often have side effects and may require increasing doses over time. The exploration of non-invasive treatments like fESWT offers potential for improved management of spasticity in this population.

Data Highlights

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Key Findings

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Clinical Implications

The combination of fESWT and BTI may enhance treatment outcomes for spasticity in MS patients, offering a non-invasive option with immediate effects. Clinicians should consider this integrative approach as part of a comprehensive management plan for spasticity.

Conclusion

The findings support the use of fESWT alongside BTI as an effective strategy for managing spasticity in multiple sclerosis, warranting further investigation and potential integration into clinical practice.

Related Resources & Content

  1. Frontiers in Neurology, 2026 -- Radial extracorporeal shock wave therapy for the management of spasticity in cerebral palsy: a randomized controlled trial with different time intervals between sessions
  2. conexiant, 2023 -- Poststroke Spasticity, Seen Too Late
  3. Knee Surgery, Sports Traumatology, Arthroscopy, 2012 -- Extracorporeal Shockwave Therapy for Tendinopathy: Technological Advances and Clinical Significance
  4. Brain, 2025 -- More is more: combining therapies to enhance spinal cord injury recovery
  5. Evidence review for pharmacological management of spasticity - NCBI Bookshelf, 2023
  6. Frontiers in Neurology, 2026 -- Extracorporeal shock wave therapy for post-stroke spasticity: an umbrella review of systematic reviews and meta-analyses
  7. Evidence review for pharmacologicalmanagement of spasticity - NCBI Bookshelf
  8. Extracorporeal shock wave therapy for post-stroke spasticity: an umbrella review of systematic reviews and meta-analyses

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