Impact of meal frequency on gastroesophageal reflux disease following laparoscopic sleeve gastrectomy - Report - MDSpire

Impact of meal frequency on gastroesophageal reflux disease following laparoscopic sleeve gastrectomy

  • By

  • Abdullah Almunifi

  • Muqrin A. Almuqrin

  • Ali Q. Al Qahtani

  • Abdullah Albarrak

  • Shiela Sadili-Fajardo

  • Abdulaziz A. AlMulhem

  • Eyad Wohaibi

  • Mohammad A. Al Mofarreh

  • June 16, 2026

  • 0 min

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Clinical Report: Influence of Meal Frequency on GERD After Laparoscopic Sleeve Gastrectomy

Overview

This study investigates the relationship between meal frequency and gastroesophageal reflux disease (GERD) symptoms in patients one year post-laparoscopic sleeve gastrectomy (LSG).

Background

Obesity is a significant health concern in Saudi Arabia, with over 35% of the population affected, leading to increased risks of GERD. LSG is a common bariatric surgery that can improve weight loss but may also exacerbate GERD symptoms in some patients. Understanding the impact of meal frequency on GERD post-LSG is crucial for optimizing patient outcomes.

Data Highlights

MeasurementPreoperative BMIPostoperative BMI
BMI46.37 kg/m²31.24 kg/m²

Key Findings

  • 109 participants (62 women, 47 men) aged 17–66 years were included in the study.
  • Primary complaints included heartburn (77.1%) and epigastric pain (70.6%).
  • Typical meal patterns postoperatively were 1–2 meals (43%) and 3–4 meals (28.4%).
  • No significant association was found between meal frequency and reflux oesophagitis (p = 0.09, 0.24, 1.00).
  • All patients experienced weight loss post-surgery.

Clinical Implications

The study suggests that meal frequency may not significantly influence GERD symptoms in patients after LSG. Clinicians should consider individual patient experiences and symptoms when advising on meal frequency postoperatively.

Conclusion

The findings indicate that larger daily meals with fewer frequent meals do not have a statistically significant association with reflux oesophagitis in patients post-LSG.

Related Resources & Content

  1. Obesity Surgery, 2020 -- Criteria for Diagnosing Gastro-esophageal Reflux After Sleeve Gastrectomy
  2. Obesity Surgery, 2023 -- Alterations in Oesophageal Transit, Macro-Reflux Events, and Gastric Emptying Associated with Enhanced Gastrointestinal Symptoms and Food Tolerance Following Sleeve Gastrectomy
  3. ASGE, 2025 -- American Society for Gastrointestinal Endoscopy guideline on the diagnosis and management of GERD: summary and recommendations
  4. SAGES, 2024 -- SAGES guidelines for the management of comorbidities relevant to metabolic and bariatric surgery
  5. Obesity Surgery — Elevated Incidence of Belching Following Sleeve Gastrectomy
  6. Obesity Surgery — Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Esophageal Function and Gastroesophageal Reflux Disease: A Prospective Analysis
  7. Surgical treatment strategies for gastroesophageal reflux after laparoscopic sleeve gastrectomy
  8. ASGE | American Society for Gastrointestinal Endoscopy guideline on the diagnosis and management of GERD: summary and recommendations
  9. SAGES guidelines for the management of comorbidities relevant to metabolic and bariatric surgery | Surgical Endoscopy | Springer Nature Link

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