Sense of Coherence in patients with stable schizophrenia: multidimensional determinants from a cross-sectional study of 438 inpatients in Guangzhou, China - Report - MDSpire

Sense of Coherence in patients with stable schizophrenia: multidimensional determinants from a cross-sectional study of 438 inpatients in Guangzhou, China

  • By

  • Rongyu Liang

  • Zangrui Niu

  • Yuanyuan Huang

  • Xiezhen Chen

  • Fengchun Wu

  • Xiaodong Chen

  • Cuixia Liu

  • Xiaolei Shi

  • Gang Zeng

  • June 15, 2026

  • 0 min

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Clinical Report: Exploring Factors Influencing Sense of Coherence in Schizophrenia

Overview

This study investigates the Sense of Coherence (SOC) among 438 stabilized schizophrenia inpatients, revealing a mean SOC score of 53.35.

Background

Schizophrenia is a chronic psychiatric disorder that significantly impacts social functioning and quality of life. Understanding the factors influencing SOC in stabilized patients is crucial for developing personalized interventions aimed at enhancing resilience and recovery. This study addresses a gap in the literature regarding SOC determinants in this population.

Data Highlights

MeasureMean ScoreStandard DeviationSample Size
SOC53.3511.81438

Key Findings

  • The mean SOC score among stabilized schizophrenia inpatients was 53.35 ± 11.81, which is lower than healthy normative values.
  • SOC positively correlated with all five dimensions of the Chinese Big Five Personality Inventory (CBF-PI).
  • Subjective social support showed a positive correlation with SOC, while objective support and support utilization had negative correlations.
  • Multiple regression identified personal income, frequency of physical activity (≥3 times/week), and having children as primary caregivers as significant predictors of SOC.
  • Stabilized schizophrenia inpatients exhibited lower SOC levels compared to healthy normative values.

Clinical Implications

Clinicians should consider the role of personal income and physical activity in enhancing SOC among schizophrenia patients. Tailored interventions, such as structured physical activity programs and enhancing subjective social support, may improve recovery outcomes.

Conclusion

The findings highlight the importance of addressing multidimensional factors influencing SOC in schizophrenia patients to enhance their resilience and recovery. Further cross-sectional and longitudinal studies are needed to validate these results and explore the underlying mechanisms.

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  5. Die neue S3-Leitlinie Schizophrenie (living) 2025 | Der Nervenarzt | Springer Nature Link
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