A rare and massive retroperitoneal leiomyoma: a case report - Report - MDSpire

A rare and massive retroperitoneal leiomyoma: a case report

  • By

  • Sujuan Jiang

  • Tingting Bai

  • Zhongwen Zou

  • Mengying Wang

  • Wenjing Xu

  • Mengze Xu

  • Kaiting Huang

  • Jie Wang

  • Mingwei Lv

  • Xue Li

  • Xiaoguang Shao

  • Jie Zhang

  • June 1, 2026

  • 0 min

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Clinical Report: A Case Study of an Uncommon Large Retroperitoneal Leiomyoma

Overview

This report details the surgical management of a rare, massive retroperitoneal leiomyoma in a 52-year-old woman, highlighting the innovative techniques used to address significant perioperative challenges. The patient's psychological distress was notably reduced postoperatively, indicating the importance of psychological support in surgical care.

Background

Retroperitoneal leiomyomas are exceptionally rare tumors that can lead to significant clinical challenges due to their size and potential for misdiagnosis. These tumors often present with vague symptoms, making early detection difficult. Understanding their management is crucial for improving patient outcomes and minimizing complications during surgical interventions.

Data Highlights

No numerical data available in the article.

Key Findings

['A 52-year-old woman presented with a giant retroperitoneal leiomyoma measuring 48×48×25 cm.', 'The tumor caused significant displacement of the right kidney and ureter, complicating surgical resection.', 'Intraoperative hemodynamic stability was maintained using a warm water bag technique during tumor removal.', 'Postoperative pathological examination confirmed the tumor as a spindle cell tumor consistent with leiomyoma.', "The patient's Hamilton Anxiety Scale score decreased from 21 to 9 postoperatively, indicating effective psychological intervention."]

Clinical Implications

This case underscores the necessity of a multidisciplinary approach in managing large retroperitoneal masses, particularly in addressing both surgical and psychological aspects of care. Clinicians should consider psychological assessments as part of the preoperative evaluation to enhance patient outcomes.

Conclusion

The successful management of this rare retroperitoneal leiomyoma illustrates the importance of innovative surgical techniques and psychological support in complex cases. Continued collaboration among healthcare professionals is essential for optimizing patient care.

Related Resources & Content

  1. Kilpatrick, S. et al., Journal of Gastrointestinal Surgery, 2013 -- Surgical Approach to Retroperitoneal Leiomyosarcoma Originating from the Inferior Vena Cava
  2. Frontiers in Oncology, 2026 -- Case Report: Intramyometrial Uterine Large-Cell Neuroendocrine Carcinoma Mimicking Adenomyosis and Leiomyomas With Rapid Fatal Relapse
  3. NCCN Guidelines® Insights: Soft Tissue Sarcoma, Version 1.2025 - PubMed
  4. Perineal Mass Due to Angioleiomyoma Arising from the Ano-Rectal Wall: A Case Study
  5. Frontiers in Surgery — Case Report: Complete endoscopic submucosal dissection for occult superficial esophageal squamous cell carcinoma concealed by a large esophageal leiomyoma
  6. A case of retroperitoneal giant leiomyoma and literature review - PMC
  7. NCCN Cl - National Comprehensive Cancer Network®
  8. NCCN Guidelines® Insights: Soft Tissue Sarcoma, Version 1.2025 - PubMed

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