Reimagining tuberculosis elimination in India: diagnostics, drug resistance, and digital health strategies - Report - MDSpire

Reimagining tuberculosis elimination in India: diagnostics, drug resistance, and digital health strategies

  • By

  • Sneha Jha

  • Loka Bikash Chaliha

  • Kshipra Pandey

  • Ritu Patel

  • June 29, 2026

  • 0 min

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Clinical Report: Innovative Approaches to Tuberculosis Control in India

Background

Tuberculosis remains a leading cause of infectious disease mortality globally, with India accounting for approximately 26% of the global TB burden. Despite efforts under the National Tuberculosis Elimination Programme (NTEP), significant barriers such as multidrug-resistant tuberculosis (MDR-TB) and healthcare inequities persist.

Data Highlights

In 2023, India reported approximately 2.7 million TB cases, accounting for nearly one-quarter of global cases. The incidence rate declined from 237 cases per 100,000 population in 2015 to approximately 187 cases per 100,000 population in 2024.

Key Findings

  • The COVID-19 pandemic disrupted TB diagnosis, treatment, and healthcare accessibility.
  • Multidrug-resistant tuberculosis (MDR-TB) continues to be a significant challenge in TB control efforts.
  • Advancements in molecular diagnostics and digital health initiatives have been implemented to strengthen TB control strategies.
  • Healthcare disparities and fragmented private healthcare systems hinder progress toward TB elimination.
  • Integrated and patient-centered approaches are necessary to address broader socioeconomic determinants affecting TB transmission.

Clinical Implications

Healthcare professionals should be aware of the ongoing challenges in TB control, particularly the impact of COVID-19 and drug resistance.

Conclusion

The review highlights the need for coordinated multisectoral approaches to accelerate TB elimination efforts in India.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Innovative Approaches to Tuberculosis Control in India
  2. DIGITAL HEALTH — Profiling digital technologies used to support the tuberculosis care cascade and their implementation across high burden countries: A systematic scoping review
  3. Frontiers in Medicine — The role of digital health interventions for adults with tuberculosis: a network meta-analysis of randomized controlled trials
  4. Infection — Cost-effective and precise identification of rifampicin and isoniazid resistance in tuberculosis sputum samples using multiplex PCR with multiple probes melting analysis
  5. Nature Medicine — Medical innovation in LMICs: can India lead the way?
  6. Profiling digital technologies used to support the tuberculosis care cascade
  7. The role of digital health interventions for adults with tuberculosis
  8. Cost-effective identification of rifampicin and isoniazid resistance
  9. Medical innovation in LMICs: can India lead the way?
  10. Key considerations in DR-TB treatment
  11. WHO consolidated guidelines on tuberculosis. Module 3: diagnosis
  12. NATIONAL GUIDELINES FOR

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