Initial evidence of effects of a novel digital behavioural treatment for chronic pain: A series of replicated randomized single-case experimental design studies - Report - MDSpire

Initial evidence of effects of a novel digital behavioural treatment for chronic pain: A series of replicated randomized single-case experimental design studies

  • By

  • Haya Al Sharaa

  • Sara Laureen Bartels

  • Patrick Onghena

  • Afra Taygar

  • Linnéa Engman

  • Ida Flink

  • Suzanne Petersson

  • Katja Boersma

  • Lance M. McCracken

  • Laura Simons

  • Johan W.S. Vlaeyen

  • Rikard K. Wicksell

  • July 14, 2026

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Clinical Report: Preliminary Findings on Digital Behavioral Intervention for Chronic Pain

Background

Chronic pain affects 20-30% of the global population and is associated with significant distress and disability. Traditional pain management strategies have limited effectiveness on health-related quality of life. Digital interventions, such as the DAHLIA project, aim to enhance access to evidence-based treatments.

Data Highlights

No numerical data or trial data was provided in the source material.

Key Findings

  • The DAHLIA program employs a digital behavioral treatment for chronic pain.
  • Daily diary methods are utilized to capture fluctuations in psychological processes during treatment.
  • The study assesses day-to-day changes in psychological flexibility and acceptance.
  • Participants serve as their own control in a replicated randomized single-case experimental design.

Clinical Implications

The findings highlight the importance of capturing within-person changes in psychological processes during treatment for chronic pain. Digital interventions may provide a scalable solution to improve access to behavioral therapies.

Conclusion

The preliminary findings from this study contribute to the understanding of digital behavioral interventions for chronic pain and support the need for further research in larger clinical trials.

Related Resources & Content

  1. Miró J, Sampietro A, Monterde S, et al., Frontiers in Digital Health, 2025 -- Correction: Development, implementation and evaluation of a digital treatment for adolescents with chronic pain: a protocol for a multi-phase study
  2. Pain Medicine, 2025 -- Forecasting Pain Outcomes Following Digital Treatment for Chronic Spinal Pain: The Impact of Disability, Employment Challenges, and Job Type in a Secondary Analysis of a Prospective Clinical Trial
  3. Journal of Medical Internet Research (JMIR), 2026 -- Combined Internet-Based Cognitive Behavioral Therapy and Face-to-Face Physiotherapy in Primary Health Care for Chronic Widespread Pain: Randomized Controlled Trial
  4. Journal of Medical Internet Research (JMIR), 2026 -- Potential of Digital Tools for Chronic Pain Management
  5. NICE, 2026 -- Digital technologies for managing non-specific low back pain: early value assessment
  6. JAMA, 2026 -- Telehealth and Online Cognitive Behavioral Therapy–Based Treatments for High-Impact Chronic Pain: A Randomized Clinical Trial
  7. Nursing Open, 2026 -- Efficacy of Internet‐Based Cognitive Behavioural Therapy (iCBT) on Pain Symptoms and Sleep Quality Improvement in Chronic Pain Patients: A Meta‐Analysis of Randomised Controlled Trials
  8. 2 The technologies | Digital technologies for managing non-specific low back pain: early value assessment | Guidance | NICE
  9. Telehealth and Online Cognitive Behavioral Therapy–Based Treatments for High-Impact Chronic Pain: A Randomized Clinical Trial | Trials | JAMA | JAMA Network
  10. Efficacy of Internet‐Based Cognitive Behavioural Therapy (iCBT) on Pain Symptoms and Sleep Quality Improvement in Chronic Pain Patients: A Meta‐Analysis of Randomised Controlled Trials - Liu - 2026 - Nursing Open - Wiley Online Library

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