Correction: Transpulmonary Driving Pressure, End-Expiratory Transpulmonary Pressure, and Pediatric ARDS Mortality

Background

Mortality rates in pediatric acute respiratory distress syndrome (ARDS) remain significant. Understanding the role of transpulmonary pressures can provide insights into patient outcomes and guide ventilation strategies.

Data Highlights

The corrected analysis included 154 patients with pediatric ARDS.

Key Findings

• Initial publication incorrectly presented Figure 1.
• 176 patients were assessed for eligibility; 22 were excluded.
• Final analysis included 154 patients.
• Mortality varied across phenotypes defined by transpulmonary driving pressure and end-expiratory transpulmonary pressure.
• End-expiratory transpulmonary pressure close to zero was not associated with favorable clinical outcomes.

Clinical Implications

Clinicians should be aware of the corrected data regarding transpulmonary pressures in pediatric ARDS.

Conclusion

The correction of the figure in this study highlights the importance of accurate data representation in clinical research.

Related Resources & Content

1. Soydan et al., Respiratory Care, 2026 -- Transpulmonary Driving Pressure, End-Expiratory Transpulmonary Pressure, and Mortality in Pediatric ARDS
2. Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2) - PMC
3. Intensive Care Medicine — Potential Misjudgment of Chest Wall Driving Pressure and Airway Closure Assessment
4. Critical Care (Springer) — Evaluation of Two Strategies for Titrating Positive End-Expiratory Pressure Based on Transpulmonary Pressure in Acute Respiratory Distress Syndrome: A Randomized Crossover Trial
5. Intensive Care Medicine — Balancing lung recruitment and venous congestion in ARDS: rethinking the systemic effects of PEEP
6. Intensive Care Medicine — Clarifying Misunderstandings in Mechanical Power Calculations for ARDS
7. Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2) - PMC
8. Transpulmonary Driving Pressure, End-Expiratory Transpulmonary Pressure, and Mortality in Pediatric ARDS.
9. Impact of Baydur ratio correction on the reliability of esophageal pressure measurement | Journal of Applied Physiology | American Physiological Society