Clinical Report: Elevated Risk of Postpartum Hemorrhage in Endometriosis

Overview

This study evaluates the risk of postpartum hemorrhage (PPH) in women with endometriosis and adenomyosis, finding a significantly higher incidence compared to controls. The study reports an unadjusted odds ratio of 8.74 for PPH in the study group.

Background

Endometriosis and adenomyosis are prevalent conditions affecting women of reproductive age, associated with various complications during pregnancy and childbirth. Postpartum hemorrhage is a leading cause of maternal morbidity and mortality, making it crucial to understand the risk factors involved. This study aims to clarify the relationship between these conditions and the incidence of PPH.

Data Highlights

Key Findings

• 11 women with endometriosis and adenomyosis experienced postpartum hemorrhage.
• The rate of PPH in the EM/AM group was 13%, compared to 1% in the control group.
• The unadjusted odds ratio for PPH in women with EM/AM was 8.74 (CI: 2.01-82.00).
• In adjusted analysis, the odds ratio was 7.56 (95% CI: 1.39-83.70, p=0.018).
• Gravidity and parity did not significantly affect the risk of PPH in the cohort.

Clinical Implications

Healthcare providers should be aware of the increased risk of postpartum hemorrhage in women with endometriosis and adenomyosis.

Conclusion

The study found a significant association between endometriosis/adenomyosis and increased risk of postpartum hemorrhage.

Related Resources & Content

1. Frontiers in Endocrinology, 2026 -- Identification of Diagnostic Blood Indicators Associated with Adenomyosis
2. Identifying Risk Factors for Significant Complications After Colorectal Surgery for Endometriosis in the United States, 2023
3. Prevalence and Clinical Characteristics of Endometriosis in 2484 Female Patients Undergoing Appendectomy for Suspected Appendicitis, 2024
4. WHO recommendations on the assessment of postpartum blood loss and use of a treatment bundle for postpartum hemorrhage, 2023
5. Randomized Trial of Early Detection and Treatment of Postpartum Hemorrhage, New England Journal of Medicine, 2023
6. the pathologist — Could Genomics Improve Endometriosis Diagnosis?
7. WHO recommendations on the assessment of postpartum blood loss and use of a treatment bundle for postpartum haemorrhage
8. Randomized Trial of Early Detection and Treatment of Postpartum Hemorrhage | New England Journal of Medicine
9. Association between adenomyosis and maternal and neonatal outcomes: a systematic review and meta-analysis