Clinical Report: Primary Diffuse Large B-Cell Lymphoma in the Rectus Abdominis Muscle

Overview

This report details a rare case of primary diffuse large B-cell lymphoma (DLBCL) in the rectus abdominis muscle of an 85-year-old female. The patient was diagnosed through ultrasound-guided biopsy and treated with an attenuated chemotherapy regimen.

Background

Primary DLBCL of the skeletal muscle is an extremely rare form of extranodal non-Hodgkin lymphoma, with primary involvement of the rectus abdominis muscle being particularly uncommon. The non-specific clinical and imaging features often lead to misdiagnosis.

Data Highlights

No numerical data or trial data available in the source material.

Key Findings

• Primary DLBCL of the rectus abdominis muscle is extremely rare and often misdiagnosed.
• The patient presented with a painful mass in the right lower abdominal wall.
• Diagnosis was confirmed through ultrasound-guided needle biopsy and immunohistochemistry.
• The patient received 4 cycles of an attenuated R-THP-COP regimen.
• Pathological biopsy combined with immunohistochemistry is the gold standard for diagnosis.
• The patient remained free of abdominal symptoms during follow-up and died from unrelated causes 3 years later.

Clinical Implications

This case highlights the importance of considering primary DLBCL in elderly patients presenting with abdominal wall masses. Accurate histopathological diagnosis is essential to avoid misdiagnosis and ensure timely treatment.

Conclusion

This case contributes to the clinical understanding of primary DLBCL in skeletal muscle.

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