Correction: Boron neutron capture therapy prolongs survival in a rat model of multifocal brain metastases - Report - MDSpire
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Correction: Prolonged Survival Observed with Boron Neutron Capture Therapy in a Rat Model of Multifocal Brain Metastases

  • By

  • Rina Shidoh-Kazuki

  • Yoshiki Fujikawa

  • Shinji Kawabata

  • Kohei Tsujino

  • Hironori Yamada

  • Fugen Takagi

  • Hideki Kashiwagi

  • Ryo Hiramatsu

  • Naosuke Nonoguchi

  • Toshihiro Takami

  • Naonori Hu

  • Takushi Takata

  • Hiroki Tanaka

  • Minoru Suzuki

  • Masahiko Wanibuchi

  • June 4, 2026

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Correction: Prolonged Survival Observed with Boron Neutron Capture Therapy

Overview

This report corrects an error in the formula presented in the original article regarding Boron Neutron Capture Therapy (BNCT) in a rat model of multifocal brain metastases. The correction clarifies the experimental design and treatment groups.

Background

Boron Neutron Capture Therapy (BNCT) is an investigational treatment modality for brain metastases. The accurate representation of experimental designs is crucial for the interpretation of clinical outcomes.

Data Highlights

No numerical or trial data presented in the correction article.

Key Findings

  • The original article contained a formula error that has been corrected.
  • BNCT is investigational for brain metastases.
  • Preclinical studies suggest BNCT can spare immune cells while inducing anti-tumor immunity.
  • BNCT received clinical approval in Japan for unresectable, locally recurrent head and neck cancer.
  • Recent studies have reported partial responses in patients with recurrent breast cancer treated with BNCT.

Clinical Implications

The correction of the formula in the experimental design is essential for accurate interpretation of BNCT's efficacy in treating brain metastases.

Conclusion

This correction emphasizes the importance of precision in scientific reporting, particularly in experimental therapies like BNCT for brain metastases.

Related Resources & Content

  1. Journal of Neuro-Oncology, 2026 -- Correction: Prolonged Survival Observed with Boron Neutron Capture Therapy in a Rat Model of Multifocal Brain Metastases
  2. Journal of Neuro-Oncology — Boron Neutron Capture Therapy for Recurrent Meningiomas: An Evaluation of Dosimetric Parameters and Clinical Outcomes
  3. Journal of Neuro-Oncology — Evolving Survival Outcomes in Non-Small Cell Lung Cancer Patients with and without Brain Metastases Undergoing Advanced Treatment Approaches
  4. The ASCO Post — Expert Point of View: Andrew B. ­Lassman, MD
  5. Journal of Neuro-Oncology — Impact of Integrating Targeted Therapies or Chemotherapy with Stereotactic Radiosurgery (SRS) on Outcomes for Patients with Brain Metastases from Non-Small Cell Lung Cancer (NSCLC)
  6. Treatment for Brain Metastases With Stereotactic Radiation vs Hippocampal-Avoidance Whole Brain Radiation: A Randomized Clinical Trial - PubMed
  7. Boron neutron capture therapy preserves immune cells and induces robust anti-tumour immunity in preclinical mouse model | Nature Communications

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