Association between extreme temperature exposure and COPD health outcomes in China: study protocol for a systematic review - Report - MDSpire

Association between extreme temperature exposure and COPD health outcomes in China: study protocol for a systematic review

  • By

  • Jiaxin Xu

  • Peng Zhang

  • Yan Wang

  • Jianya Yang

  • Suyun Li

  • June 25, 2026

  • 0 min

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Clinical Report: Examining the Link Between Extreme Temperature Exposure and COPD Outcomes in China

Overview

This systematic review aims to assess the relationship between extreme temperature exposures and COPD health outcomes in Chinese populations. It will include observational studies to evaluate the impact of heat and cold on COPD-related mortality and morbidity.

Background

Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide, with significant prevalence in China. The increasing frequency of extreme temperature events due to climate change poses a potential risk to COPD patients.

Key Findings

  • The systematic review will utilize the PECOS framework to assess the impact of extreme temperatures on COPD outcomes.
  • Heat exposure has been linked to increased risk of respiratory diseases, including COPD.
  • Cold exposure has been associated with a higher risk of COPD-related mortality compared to heat exposure.
  • Previous studies in high-income countries indicate significant associations between temperature extremes and COPD incidence and mortality.
  • The review aims to fill the knowledge gap regarding the effects of extreme temperatures on COPD in the Chinese population.

Clinical Implications

This systematic review seeks to evaluate the relationship between extreme temperature exposure and COPD outcomes in China.

Conclusion

This systematic review seeks to comprehensively evaluate the relationship between extreme temperature exposure and COPD outcomes in China, addressing a critical gap in current research.

Related Resources & Content

  1. BMC Psychiatry, 2025 -- Impact of Environmental Temperature on Mortality Rates in Community-Dwelling Individuals with Severe Mental Illness: A Time-Stratified Case-Crossover Analysis in Western China
  2. European Journal of Preventive Cardiology, 2025 -- Incidence and burden of cardiovascular disease attributable to extreme heat in China
  3. American Journal of Epidemiology, 2025 -- Impact of Chronic PM2.5 Exposure on Peak Expiratory Flow Among Middle-Aged and Elderly Individuals in China: A Quasi-Experimental Analysis
  4. Global Initiative for Chronic Obstructive Lung Disease 2025 Report -- GOLD 2025 Report
  5. Extreme temperature increases the risk of COPD morbimortality: A systematic review and meta-analysis, 2025 -- ScienceDirect
  6. The Journal of Clinical Endocrinology & Metabolism — The Link Between Air Pollution and Diabetes Mellitus: An Investigation in a Desert Region of China
  7. Global Initiative for Chronic Obstructive Lung Disease 2025 Report
  8. Extreme temperature increases the risk of COPD morbimortality: A systematic review and meta-analysis - ScienceDirect
  9. Prevalence of Chronic Obstructive Pulmonary Disease in Adults Aged 40 Years and Older in China From 2014 to 2024: A Systematic Review and Meta-Analysis - Yinxia Luo, Fang Wang, Xia Zeng, Sufang Tan, Liwen Xiang, Shuwen Pang, Xiaoxuan Guo, Xiaorong Mao, 2025

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