Covid vaccination cut risk of adverse heart events, large study finds
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By
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Lauren Chan
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June 15, 2026
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0 min
Clinical Report: COVID Vaccination Associated with Decreased Incidence of Adverse Cardiac Events
Overview
A large-scale study found that recent COVID vaccination is associated with a reduction in adverse cardiac events, including heart attacks and strokes, among vaccinated individuals. The study reports a 38% lower risk of COVID-associated major cardiovascular events and a 24% reduction in all-cause cardiac events.
Background
The relationship between COVID-19 infection and increased risk of adverse cardiac events is documented. Understanding the cardioprotective effects of COVID vaccination is crucial, especially as vaccination rates among high-risk populations remain low.
Data Highlights
The study followed over one million veterans, revealing:
- 38% lower risk of COVID-associated major cardiovascular events in vaccinated individuals.
- 24% reduction in all-cause cardiac events among vaccinated individuals.
- Potential prevention of approximately 3,500 major cardiac events and 2,400 deaths annually per one million vaccinated individuals.
Key Findings
- COVID vaccination was associated with a 38% reduction in COVID-related major cardiovascular events.
- Vaccination led to a 24% reduction in all-cause cardiac events.
- Benefits were observed in individuals aged 75 and older and those with chronic conditions.
- Vaccine-related myocarditis is milder than myocarditis from COVID infection.
- COVID vaccine uptake in seniors is less than half that of flu vaccines.
Clinical Implications
Healthcare professionals should consider the cardioprotective effects of COVID vaccination when discussing vaccination with patients at higher risk for cardiovascular events.
Conclusion
The findings from this study highlight a public health opportunity regarding COVID vaccination and adverse cardiac events.
Related Resources & Content
- Ziyad Al-Aly, JAMA Internal Medicine, 2024 -- COVID Vaccination Associated with Decreased Incidence of Adverse Cardiac Events
- conexiant, Flu Vaccination Linked to Lower Heart, Stroke Risk After Infection, 2024
- Clinical Research in Cardiology, Assessment of Carditis Incidence in Pediatric and Adolescent Populations Following COVID-19 Vaccination: A Systematic Review and Meta-Analysis, 2022
- Clinical Research in Cardiology, Ventricular Arrhythmia Incidence in ICD Patients During the COVID-19 Pandemic's Second Wave, 2023
- CDC, 2025–2026 COVID-19 Vaccination Guidance, 2025
- European Journal of Preventive Cardiology — Cardiovascular disease prevention and management in COVID-19: a clinical consensus statement of the European Association of Preventive Cardiology, the European Association of Cardiovascular Imaging, the Association of Cardiovascular Nursing & Allied Professions, the European Association of Percutaneous Cardiovascular Interventions, and the Heart Failure Association of the ESC
- Some acute and chronic viral infections may increase the risk of cardiovascular disease
- 2025–2026 COVID-19 Vaccination Guidance | Covid | CDC
- Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans | New England Journal of Medicine
This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.
