Clinical Report: Multimodal Imaging Techniques in Vascular Medicine

Overview

This case study presents a 27-year-old man with adventitial cystic disease affecting the superficial femoral artery, diagnosed through multimodal imaging techniques. The findings highlight the importance of recognizing characteristic imaging features to differentiate ACD from atherosclerotic disease.

Background

Adventitial cystic disease (ACD) is a rare, nonatherosclerotic vascular disorder that can lead to significant luminal compression and is often misdiagnosed. Its typical presentation includes exertional claudication in young, otherwise healthy individuals, making accurate diagnosis crucial for appropriate management. Multimodal imaging plays a vital role in identifying ACD and guiding surgical intervention.

Data Highlights

No numerical data or trial data presented.

Key Findings

• A 27-year-old man presented with exertional calf pain and diminished pulses.
• Duplex ultrasonography revealed significant stenosis in the left superficial femoral artery.
• Computed tomography angiography showed segmental luminal narrowing without calcification.
• Magnetic resonance imaging confirmed the diagnosis of adventitial cystic disease with characteristic cystic features.
• Histopathology indicated a degenerative process with mucin-filled cystic spaces.

Clinical Implications

Recognition of ACD's imaging characteristics is essential for differentiating it from atherosclerotic disease. This case underscores the need for multimodal imaging in young patients presenting with atypical claudication symptoms.

Conclusion

The case illustrates the diagnostic utility of multimodal imaging in identifying adventitial cystic disease, emphasizing the importance of accurate diagnosis for effective management.

Related Resources & Content

1. Frontiers in Surgery, 2026 -- Experience in the Diagnosis and Treatment of Venous Adventitial Cystic Disease: Case Series and Literature Review
2. European Radiology, 2023 -- Vascular Imaging Based on Position and Posture: A Comprehensive Review
3. 2024 AHA/ACC Peripheral Artery Disease Guideline
4. Comprehensive Investigation of the Wall Structure in Intracranial Aneurysms
5. Pediatric Cardiology — Two Instances of Cardiac Arteriovenous Malformation Associated with a Localized Angioproliferative Condition
6. Cystic adventitial disease of the common femoral artery: a case report and overview of the literature
7. Cystic Adventitial Disease of the (ilio) Femoral Artery with a Connection to the Hip Joint: Case Report and a Review of the Literature
8. 2024 AHA/ACC Peripheral Artery Disease Guideline