Angiographic Insights from Optical Coherence Tomography in Attention Deficit Hyperactivity Disorder - Report - MDSpire
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Angiographic Insights from Optical Coherence Tomography in Attention Deficit Hyperactivity Disorder

  • By

  • Hany Mahmoud

  • Mohamed Salah Hamed Korishy

  • Ahmed Ezzat Amin

  • Islam Awny

  • Dalia Tohamy

  • December 19, 2025

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Clinical Report: Angiographic Insights from Optical Coherence Tomography in ADHD

Overview

This study investigates retinal thickness and vascular abnormalities in adult ADHD patients using optical coherence tomography (OCT) angiography. Findings suggest significant differences in retinal vascular density between ADHD patients and control subjects.

Background

Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder affecting approximately 2.5% of the global population. The condition is characterized by inattention and hyperactivity, with potential genetic and environmental etiologies. Recent studies have indicated possible retinal abnormalities in ADHD patients, suggesting a link between retinal health and neurodevelopmental disorders.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • ADHD patients exhibited altered retinal thickness compared to normal controls.
  • Significant differences in vascular density were observed in the macula and peripapillary areas of ADHD patients.
  • The study included a sample size of 50 ADHD patients and 50 controls, ensuring robust comparative analysis.
  • OCT angiography was utilized as a non-invasive method to assess retinal structure and vascularity.
  • Participants were carefully selected based on strict inclusion and exclusion criteria to ensure the validity of results.

Clinical Implications

The findings highlight the potential for OCT angiography as a tool for assessing retinal changes in ADHD patients, which may contribute to understanding the neurobiological underpinnings of the disorder. Clinicians should consider the implications of retinal health in the management of ADHD.

Conclusion

This study underscores the relationship between ADHD and retinal abnormalities, suggesting that OCT angiography may provide valuable insights into the disorder's neurobiological aspects.

Related Resources & Content

  1. Retinal Physician, Source, 2021 -- OCT and OCTA in Alzheimer Disease
  2. BMC Psychiatry, Source, 2025 -- Altered auditory attention and functional connectivity in the auditory cortex of children with Attention-Deficit/Hyperactivity Disorder
  3. BMC Psychiatry, Source, 2025 -- Transdiagnostic eye-tracking biomarkers of inattention across psychiatric disorders: a systematic review
  4. NICE, Source, 2025 -- Overview | Attention deficit hyperactivity disorder: diagnosis and management
  5. PMC, Source, 2023 -- Retinal Thinning in Attention Deficit Hyperactivity Disorder (ADHD): Structural Changes Detected by Spectral-Domain OCT
  6. BMC Psychiatry (Springer) — Brain–behavior relationships in task-based fMRI assessments of executive functions in children and adolescents with and without ADHD: a systematic review and ALE meta-analysis
  7. Overview | Attention deficit hyperactivity disorder: diagnosis and management | Guidance | NICE
  8. Retinal Thinning in Attention Deficit Hyperactivity Disorder (ADHD): Structural Changes Detected by Spectral-Domain OCT - PMC
  9. Frontiers | Quantitative ophthalmic posterior segment optical coherence tomography angiography and neurologic conditions: a review

Original Source(s)

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