Impact of the COVID-19 Pandemic on the Incidence of Retinal Vascular Occlusions: An Epidemiological Analysis - Report - MDSpire

Impact of the COVID-19 Pandemic on the Incidence of Retinal Vascular Occlusions: An Epidemiological Analysis

  • By

  • Andrea Montesel

  • Yan Guex-Crosier

  • Chiara M. Eandi

  • April 27, 2026

  • 0 min

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Clinical Report: Impact of the COVID-19 Pandemic on Retinal Vascular Occlusions

Overview

This study evaluated the incidence of retinal vascular occlusions during the COVID-19 pandemic. Findings indicate no significant increase in retinal vein or artery occlusions in 2020 compared to 2019, challenging previous assumptions about the pandemic's impact on ocular health.

Background

The COVID-19 pandemic has raised concerns regarding its systemic vascular complications, including retinal vascular occlusions. Understanding the incidence of these events during the pandemic is crucial for healthcare professionals to manage and anticipate potential ocular complications in patients. This study provides valuable population-level data to inform clinical practice.

Data Highlights

YearCRVOBRVOCRAOBRAO
20193828911
20203415147

Key Findings

  • No significant increase in retinal vein occlusions (IRR 0.73, p=0.093) during the pandemic.
  • Arterial occlusions showed no significant change (IRR 1.04, p=0.896).
  • Monthly analysis revealed no significant correlation between COVID-19 case counts and retinal vascular events (p=0.08).
  • The study focused on a population exposed only to natural COVID-19 infection, excluding vaccination effects.
  • Findings challenge previous reports suggesting a strong association between COVID-19 and retinal vascular occlusions.

Clinical Implications

Healthcare professionals should be aware that the incidence of retinal vascular occlusions did not increase during the early phase of the COVID-19 pandemic. This information may influence clinical decision-making and patient management strategies regarding ocular health during viral outbreaks.

Conclusion

The study provides evidence that the COVID-19 pandemic did not lead to an increased incidence of retinal vascular occlusions, which may alleviate some concerns regarding ocular complications associated with the virus.

References

  1. Retinal Physician, Effects of COVID-19 Infection and Vaccination in the Retina, 2023 -- https://retinalphysician.com/issues/2023/october/effects-of-covid-19-infection-and-vaccination-in-the-retina/
  2. Retinal Physician, Retinal Disease Prevalence Study Reveals Gaps, 2026 -- https://www.retinalphysician.com/issues/2026/march-april/retinal-disease-prevalence-study-reveals-gaps/
  3. PubMed, Retinal Vein Occlusions Preferred Practice Pattern®, 2023 -- https://pubmed.ncbi.nlm.nih.gov/39918523/?utm_source=openai
  4. Retinal Physician — Effects of COVID-19 Infection and Vaccination in the Retina
  5. retinal physician — Retinal Disease Prevalence Study Reveals Gaps
  6. Retinal Physician — Retinal Disease Prevalence Study Reveals Gaps
  7. Infection — Impact of SARS-CoV-2 Infection on Chronic Kidney Disease Patients Undergoing Dialysis: Analysis Across Various Pandemic Phases and Its Influence on Mortality Rates
  8. Retinal Vein Occlusions Preferred Practice Pattern® - PubMed
  9. Ranibizumab for macular edema following central retinal vein occlusion: six-month primary end point results of a phase III study - PubMed
  10. Ophthalmic complications associated with COVID-19: a large US national database analysis | Eye

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