Novel two-stage deep learning framework for automated pressure injury classification - Report - MDSpire
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Innovative Two-Phase Deep Learning System for Automated Classification of Pressure Injuries

  • By

  • Ting-Yu Lai

  • Yi-Jiun Chou

  • Chun-You Liu

  • Chien-Wei Chen

  • Ching-Ting Lin

  • Wei-Chun Wang

  • Yimin Hsu

  • Ming-Li Hsieh

  • Shih-Sheng Chang

  • March 27, 2026

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Clinical Report: Innovative Two-Phase Deep Learning System for Automated Classification of Pressure Injuries

Overview

This study presents a two-stage deep learning framework for automatic pressure injury staging from clinical images, achieving high accuracy and reliability. The system integrates YOLOv9 for lesion detection and DenseNet161 for classification.

Background

Pressure injuries (PIs) are a significant concern in hospitalized patients, often leading to adverse outcomes and increased healthcare costs. Accurate staging of PIs is crucial for effective management, yet traditional methods are subjective and can result in misclassification. The development of an objective, AI-driven classification system could improve the reliability of PI assessments.

Data Highlights

MetricValue
mAP@0.5 (YOLOv9)0.796
Overall Accuracy (Staging Model)0.775
Sensitivity0.775
Specificity0.955
Precision0.779
F1 Score0.775

Key Findings

  • The two-stage AI framework integrates YOLOv9 for lesion detection and DenseNet161 for staging classification.
  • The object detection model achieved an mAP@0.5 of 0.796.
  • The staging model demonstrated an overall accuracy of 0.775 on an independent test set.
  • Sensitivity and specificity of the staging model were 0.775 and 0.955, respectively.
  • The framework improves clinical interpretability and reduces background noise in image analysis.
  • Challenges remain in addressing intra-wound heterogeneity and variability in image quality.

Clinical Implications

The proposed AI system provides standardized and reproducible PI staging from clinical images.

Conclusion

This innovative two-stage AI framework aims to improve the accuracy of pressure injury staging.

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- Development and preliminary clinical validation of a mobile health application for pressure injury staging in ICU patients
  2. DIGITAL HEALTH, 2026 -- Enhancing clinical reliability in pressure injury prediction: A conformal prediction approach with machine learning models
  3. Frontiers in Medicine, 2026 -- Integrating anisotropic heat flow and transformer encoders in convolutional neural network for skin cancer classification
  4. Frontiers in Medicine, 2026 -- A predictive nomogram for in-ICU deterioration of stage 1 pressure injuries: a retrospective study
  5. Skin and Tissue Assessment, International Guideline
  6. Cochrane Library, Cochrane Database of Systematic R -- Pressure Injury Stages
  7. Pressure Injury Stages - National Pressure Ulcer Advisory Panel
  8. Skin and Tissue Assessment — International Guideline
  9. Cochrane Library Cochrane Database of Systematic R
  10. Pressure Injury Stages - National Pressure Ulcer Advisory Panel

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