Epidemiology of bone cancer in Saudi Arabia: a nationwide population-based study (2004–2020) - Report - MDSpire

Epidemiology of bone cancer in Saudi Arabia: a nationwide population-based study (2004–2020)

  • By

  • Ibrahim G. Alghamdi

  • Hasan A Alaidarous

  • Murad I Alghamdi

  • Khalid A Alghamdi

  • Musharraf A Alghamdi

  • Mazen S Alghamdi

  • Anas A Alzahrani

  • Tariq A Alghamdi

  • Osama M Alomari

  • Khalid S Alghamdi

  • Mohammed M Alzahrani

  • Ragad A Alzahrani

  • Hazim H Alsadi

  • June 26, 2026

  • 0 min

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Clinical Report: National Epidemiological Analysis of Bone Cancer in Saudi Arabia

Overview

This study provides a comprehensive analysis of bone cancer incidence in Saudi Arabia from 2004 to 2020, revealing a total of 2,275 cases with a male predominance and a notable adolescent peak in incidence. Regional variations in age-standardized incidence rates (ASIRs) across the country were observed.

Background

Bone cancer is a rare malignancy with varying incidence patterns influenced by age, sex, and geography. This study addresses the gap in comprehensive population-based data on bone cancer in the region.

Data Highlights

YearTotal CasesMale CasesFemale Cases
2004-202022751318 (57.9%)957 (42.1%)

Key Findings

  • Total of 2,275 primary bone cancer cases recorded from 2004 to 2020.
  • Bone cancer accounted for approximately 2.0% of all cancers among males and 0.9% among females.
  • Mean age-standardized incidence rates (ASIRs) were higher in males (≈1.0 per 100,000) than in females (≈0.7 per 100,000).
  • Age-specific incidence peaked in adolescents, particularly in the 15–19-year age group.
  • Regional variations in ASIRs were noted, with higher rates in Al-Jouf and Najran.
  • Cumulative incidence rates (CIRs) remained below 2.0 per 100,000 throughout the study period.

Clinical Implications

The findings underscore the need for enhanced cancer surveillance in Saudi Arabia to monitor bone cancer trends and inform healthcare planning. Understanding the demographic and regional variations can aid in targeted public health interventions.

Conclusion

This study highlights the rarity of bone cancer in Saudi Arabia while revealing significant variations in incidence by sex, age, and region.

Related Resources & Content

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  16. Frontiers | Epidemiology of Bone Cancer in Saudi Arabia: A Nationwide Population-Based Study (2004–2020)
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