Correction: CTE-type tau filaments in Alzheimer’s disease with co-morbid LATE-NC - Report - MDSpire
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Erratum: Presence of CTE-like tau filaments in Alzheimer’s disease accompanied by LATE-NC

  • By

  • Jaimin K. Rana

  • Emile S. Pinarbasi

  • Martin G. Fernandez

  • Vikas Navratna

  • Kyle S. Conway

  • Andrew P. Lieberman

  • Sami J. Barmada

  • Shyamal Mosalaganti

  • August 20, 2026

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Clinical Report: Erratum: Presence of CTE-like tau filaments in Alzheimer’s disease

Background

Alzheimer’s disease (AD) is a leading cause of neurodegenerative pathology characterized by amyloid-β plaques and tau neurofibrillary tangles. Recent findings suggest that a significant number of individuals diagnosed with AD may also exhibit co-morbid conditions such as limbic-predominant age-related TDP-43 encephalopathy (LATE-NC), complicating diagnosis and treatment.

Data Highlights

No numerical or trial data is presented in the erratum.

Key Findings

  • The original article published in Acta Neuropathologica contained five supplementary tables that were incorrectly included in the main text.
  • The correction notice clarifies that these tables have been removed from the published version.
  • CTE-type tau filaments have been identified in cases of Alzheimer’s disease with co-morbid LATE-NC.
  • Recent literature emphasizes the importance of recognizing LATE-NC as a common co-pathology in late-life neurodegenerative diseases.
  • Diagnostic criteria for LATE have been proposed to standardize recognition when co-morbid with ADNC.

Clinical Implications

The correction of the article ensures that the scientific community has accurate information regarding the structural features of tau filaments in Alzheimer’s disease.

Conclusion

The erratum serves to clarify previously published information regarding tau filaments in Alzheimer’s disease.

Related Resources & Content

  1. Acta Neuropathologica, 2026 -- Erratum: Presence of CTE-like tau filaments in Alzheimer’s disease
  2. Acta Neuropathologica, 2022 -- Erratum: Classification of Pathogenic Tau, α-Synuclein, and TDP-43 Based on Ultrastructural and Biochemical Features
  3. Acta Neuropathologica, 2026 -- Molecular signatures and biomarker development for limbic-predominant age-related TDP-43 encephalopathy (LATE)
  4. Journal of Neuropathology & Experimental Neurology, 2026 -- Clinical, genetic, and neuropathologic correlates of LATE-NC: A systematic review and meta-analysis
  5. ScienceDirect, 2026 -- Joint EANM/SNMMI recommendations on the use of Tau PET imaging in Alzheimer's disease
  6. Acta Neuropathologica — Erratum: Cryo-EM Analysis of Tau Filaments in Alzheimer's Disease Utilizing PET Ligand APN-1607
  7. Clinical, genetic, and neuropathologic correlates of limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC): A systematic review and meta-analysis | Journal of Neuropathology & Experimental Neurology | Oxford Academic
  8. Joint EANM/SNMMI recommendations on the use of Tau PET imaging in Alzheimer's disease - ScienceDirect
  9. Tau positron emission tomography results from TOGETHER, a double‐blind, placebo‐controlled Phase II study of bepranemab in prodromal–mild Alzheimer’s disease - PMC

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