Correlations between multiple obesity diagnostic criteria and fracture risk as well as cardiovascular diseases in patients with diabetes mellitus - Report - MDSpire
Advertisement
Associations of Various Obesity Assessment Methods with Fracture Risk and Cardiovascular Disease in Diabetic Patients
Clinical Report: Associations of Various Obesity Assessment Methods with Fracture Risk
Overview
This study evaluates the associations between different obesity diagnostic criteria and the risks of cardiovascular disease (CVD) and fractures in diabetic patients.
Background
Obesity is a growing global health concern, particularly among individuals with diabetes, who face increased risks of complications such as cardiovascular disease and fractures.
Data Highlights
Metric
Change
High BMI in China (1990-2021)
Increased by 146.22%
Global High BMI Increase
Increased by 70.89%
WHtR and CVD Risk (Highest vs. Lowest Tertile)
OR = 1.14 (95% CI: 1.04–1.25)
WHtR and Hip Fracture Risk (Highest vs. Lowest Tertile)
OR = 1.83 (95% CI: 1.41–2.62)
Key Findings
The age-standardized rate of high BMI in China increased by 146.22% from 1990 to 2021.
EASO criteria showed significant associations with cardiovascular disease in the diabetic cohort.
WHtR was a significant risk factor for both cardiovascular disease and hip fractures across all models.
Higher WHtR tertiles were associated with increased risks of CVD and hip fractures, indicating a dose-response relationship.
Restricted cubic spline models confirmed that risk increases with rising WHtR.
Clinical Implications
This study presents findings related to waist-to-height ratio in the context of obesity-related comorbidities in diabetic patients.
Conclusion
The rising burden of high BMI, particularly in China, is highlighted in this study.
