15 new drugs added to Medicare price negotiations
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By
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John Wilkerson
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January 27, 2026
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0 min
Fifteen Additional Medications Included in Medicare Price Negotiation Process
Overview
The Trump administration announced 15 additional drugs subject to Medicare price negotiation, marking the first inclusion of physician-administered drugs under Part B. These negotiated prices will take effect in 2028 and aim to reduce costs for expensive medications, including several cancer and HIV treatments.
Background
Medicare price negotiation is a policy designed to lower drug costs for Medicare beneficiaries by allowing the government to negotiate prices directly with manufacturers. Previously, only retail drugs covered under Part D were eligible, but this is the first year physician-administered drugs under Part B are included. Some drugs, especially those in protected classes like cancer and HIV therapies, are expected to yield significant savings due to current rebate negotiation challenges. The program reflects a shift in drug pricing strategy under the Trump administration, despite political opposition.
Data Highlights
| Drug | Indication | Manufacturer |
|---|---|---|
| Anoro Ellipta | Chronic obstructive pulmonary disease | GSK |
| Biktarvy | HIV | Gilead Sciences |
| Botox and Botox Cosmetic | Cosmetic and therapeutic uses including chronic migraines | AbbVie |
| Cimzia | Rheumatoid arthritis, Crohn’s disease, autoimmune conditions | UCB |
| Cosentyx | Autoimmune conditions including plaque psoriasis | Novartis |
| Entyvio | Ulcerative colitis and Crohn’s disease | Takeda |
| Erleada | Prostate cancer | Janssen Biotech |
| Kisqali | Breast cancer | Novartis |
| Lenvima | Advanced cancers | Eisai |
| Orencia | Rheumatoid arthritis and psoriatic arthritis | Bristol Myers Squibb |
| Rexulti | Schizophrenia | Otsuka Pharmaceuticals |
| Trulicity | Cardiovascular diseases | Eli Lilly |
| Verzenio | Breast cancer | Eli Lilly |
| Xeljanz and Xeljanz XR | Rheumatoid arthritis and inflammatory conditions | Pfizer |
| Xolair | Asthma and allergic reactions | Genentech |
Key Findings
- Fifteen drugs were added to the Medicare price negotiation list, including the first physician-administered drugs under Part B.
- Negotiated prices will be implemented starting in 2028.
- Several included drugs are for cancer and HIV, which are protected classes under Medicare and may yield substantial savings.
- Physician-administered drugs pose data challenges due to incomplete pricing information from Medicare Advantage plans.
- The list includes drugs for autoimmune diseases, cardiovascular conditions, schizophrenia, and asthma.
- The Trump administration emphasized targeting the most expensive Medicare drugs to negotiate fair prices.
Clinical Implications
Clinicians should be aware that drug costs for these 15 medications may decrease starting in 2028 due to Medicare negotiations, potentially improving patient access and adherence. The inclusion of physician-administered drugs may also impact treatment planning and reimbursement processes. Awareness of these changes can aid in patient counseling regarding medication affordability.
Conclusion
The expansion of Medicare price negotiation to include physician-administered drugs represents a significant policy development aimed at reducing drug costs for beneficiaries. This initiative may lead to broader access and financial relief for patients requiring high-cost therapies.
References
- Centers for Medicare and Medicaid Services Press Release
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