Estimation of populations at risk for severe influenza and vaccination coverage in Mexico, 2010–2021 - Report - MDSpire

Assessment of High-Risk Populations for Severe Influenza and Vaccination Rates in Mexico from 2010 to 2021

  • By

  • Arturo Galindo-Fraga

  • Gerardo Luna-Casas

  • Ricardo Gasca-Pineda

  • Gilberto Sánchez-González

  • July 21, 2026

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Clinical Report: Assessment of High-Risk Populations for Severe Influenza in Mexico

Overview

This study estimates the size of populations eligible for influenza vaccination in Mexico and evaluates vaccination coverage gaps among at-risk populations from 2010 to 2021. Approximately 12.5 million vaccine doses were administered in 2021.

Background

Influenza poses a substantial risk of morbidity and mortality, particularly among individuals with underlying health conditions. Understanding vaccination coverage among high-risk populations is crucial for public health planning.

Data Highlights

No specific numerical data or trial data presented in the article.

Key Findings

  • Healthcare service utilization among at-risk populations was consistently lower than notified cases and prevalence estimates.
  • Vaccination coverage varied significantly across different at-risk populations and remained incomplete from 2010 to 2021.
  • In 2021, around 12.5 million influenza vaccine doses were administered.
  • Forecasting analyses indicated a progressive increase in healthcare demand among at-risk populations over time.
  • Gaps exist between estimated at-risk populations, diagnosed individuals, healthcare utilization, and vaccination coverage.

Clinical Implications

Healthcare providers should be aware of the gaps in influenza vaccination coverage among high-risk populations in Mexico.

Conclusion

The study identifies gaps between estimated at-risk populations, diagnosed individuals, healthcare utilization, and vaccination coverage in Mexico.

Related Resources & Content

  1. JAMA Network Open, 2024 — Influenza Vaccine and Associated Infection and Death in California, 2024 to 2025
  2. The Journal of Infectious Diseases, 2018 — Influenza Vaccine-Averted Illness in Chile, Guyana, and Paraguay During 2013–2018
  3. The Journal of Infectious Diseases, 2018 — Annual Estimation of Seasonal Influenza Burden in 6 South American Countries
  4. JAMA Network Open, 2023 — Influenza Vaccination Trends Among Children and Adolescents, 2017-2023
  5. Lineamientos Temporada invernal 2025-2026_Vf, 2025 — National Guidance for Seasonal Influenza Vaccination
  6. WHO, 2024 — Clinical practice guidelines for influenza
  7. Lineamientos Temporada invernal 2025-2026_Vf
  8. Clinical practice guidelines for influenza
  9. Efficacy of influenza vaccines and its relationship with immunological surrogate endpoints: a systematic review and meta-analysis of randomized controlled trial - ScienceDirect

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