Erector spinae plane block for opioid sparing in children undergoing laparoscopic appendectomy: a randomized controlled trial - Report - MDSpire

Erector spinae plane block for opioid sparing in children undergoing laparoscopic appendectomy: a randomized controlled trial

  • By

  • Ming-wen Yang

  • Yu-zhu Cai

  • Ling-li Zhang

  • Jun Wang

  • Ran Tang

  • Ying-ying Sun

  • May 1, 2026

  • 0 min

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Clinical Report: Erector Spinae Plane Block's Role in Reducing Opioid Use for Pediatric Laparoscopic Appendectomy

Overview

This study evaluates the efficacy of erector spinae plane block (ESPB) in reducing opioid consumption and managing postoperative pain in children undergoing laparoscopic appendectomy. Results indicate a significant reduction in opioid use and improved pain management without increasing adverse events.

Background

Postoperative pain management in children following laparoscopic appendectomy is critical, as inadequate pain control can lead to prolonged recovery and increased hospital stays. The erector spinae plane block (ESPB) has shown promise in other surgical contexts, but its role in laparoscopic procedures in pediatrics remains underexplored. This study aims to fill that gap by assessing the analgesic benefits and safety of ESPB in this population.

Data Highlights

OutcomeESPB GroupControl GroupP-value
24 h hydromorphone consumption (μg/kg)32.8 ± 10.172.9 ± 14.5< 0.001
Pain scores (PACU to 6 h)LowerHigher< 0.05
Time to first PCIA demand (min)201.058.5< 0.001
Total PCIA presses1017< 0.001
Rescue analgesia requirements2.7%21.1%0.028
Parental satisfaction score870.001

Key Findings

  • The ESPB group had a 55% reduction in 24 h hydromorphone consumption compared to the control group.
  • Lower pain scores were observed in the ESPB group during the early postoperative period.
  • Time to first patient-controlled intravenous analgesia (PCIA) demand was significantly longer in the ESPB group.
  • Fewer total and effective PCIA presses were required in the ESPB group.
  • Lower rates of rescue analgesia were needed in the ESPB group.
  • No serious complications related to the block were reported.

Clinical Implications

The findings support the use of ESPB as an effective component of multimodal analgesia for pediatric laparoscopic appendectomy, potentially reducing opioid consumption and improving pain management. Clinicians should consider incorporating ESPB into their postoperative care protocols for this patient population.

Conclusion

The study demonstrates that bilateral ultrasound-guided ESPB significantly reduces opioid use and enhances postoperative pain management in children undergoing laparoscopic appendectomy, with a favorable safety profile.

References

  1. Obesity Surgery, Springer, 2025 -- Comparison of Erector Spinae Plane Block and Intravenous Lidocaine in Opioid-Free Anesthesia for Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Trial
  2. Obesity Surgery, 2025 -- The Effect of Erector Spinae Plane Block on Diaphragmatic Function After Laparoscopic Sleeve Gastrectomy in Patients with Morbid Obesity: A Double-Blind Randomized Controlled Study
  3. APPENDICECTOMY -- Summary recommendations for appendicectomy
  4. Erector spinae plane block for analgesia in children undergoing surgery: A systematic review, meta-analysis and trial sequential analysis - ScienceDirect, 2025
  5. Response to the editorial on "Comparative analysis of two-stage laparoscopic transversus abdominis plane block versus thoracic epidural anesthesia in bowel resection—an exploratory cohort investigation
  6. Obesity Surgery — Evaluation of Ultrasound-Assisted External Oblique Intercostal Plane Block for Managing Postoperative Pain Following Laparoscopic Sleeve Gastrectomy: A Prospective, Randomized, Controlled Study with Blinded Patients and Observers
  7. Erector Spinae Plane Block in Pediatric Surgery
  8. Erector spinae plane block for analgesia in children undergoing surgery: A systematic review, meta-analysis and trial sequential analysis - ScienceDirect
  9. Erector spinae plane block in laparoscopic colorectal surgery for reducing opioid requirement and facilitating early ambulation: a double-blind, randomized trial - PMC

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