Outcomes of Phacoemulsification and Trabeculectomy for Uncontrolled Glaucoma and Cataract: A Comparison of Staged and Combined Techniques in a Single-Center Observational Study - Report - MDSpire
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Outcomes of Phacoemulsification and Trabeculectomy for Uncontrolled Glaucoma and Cataract: A Comparison of Staged and Combined Techniques in a Single-Center Observational Study

  • By

  • Matteo Sacchi

  • Gianluca Monsellato

  • Davide Rastelli

  • Shadan Ranaei

  • Davide Tomaselli

  • Gaia Li Calzi

  • Edoardo Villani

  • Stefano Dore

  • Antonio Pinna

  • Paolo Nucci

  • February 9, 2026

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Outcomes of Phacoemulsification and Trabeculectomy for Uncontrolled Glaucoma

Overview

This study compares the outcomes of staged versus combined surgical techniques for patients with uncontrolled glaucoma and cataract over a four-year follow-up period. The findings indicate that while both approaches significantly reduce intraocular pressure (IOP), the staged approach may offer better long-term IOP control and procedural success rates.

Background

Cataract and glaucoma are leading causes of blindness, often coexisting in patients, complicating treatment strategies. Effective management of these conditions is crucial for preserving vision and quality of life. Surgical options include staged or combined approaches, yet there is no consensus on the optimal technique, necessitating further investigation into their long-term outcomes.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • Both staged and combined surgical approaches significantly decreased IOP in patients with uncontrolled glaucoma and cataract.
  • The staged approach resulted in lower mean IOP compared to the combined approach.
  • Patients undergoing staged surgery had less requirement for bleb needling and higher procedural success rates.
  • Previous studies have shown conflicting results regarding the efficacy of staged versus combined techniques.
  • Long-term follow-up is essential to assess the maintenance of IOP control post-surgery.

Clinical Implications

Surgeons should consider individual patient factors when deciding between staged and combined surgical approaches for cataract and glaucoma. The staged approach may be preferable for achieving better long-term IOP control and reducing the need for additional interventions.

Conclusion

The choice between staged and combined surgical techniques for managing cataract and uncontrolled glaucoma should be guided by individual patient circumstances, with evidence suggesting that staged surgery may offer superior outcomes in terms of IOP control.

Related Resources & Content

  1. Ophthalmology Management, 2016 -- The in-tandem surgical dilemma
  2. Retinal Physician, 2024 -- Combined Phacovitrectomy Surgery
  3. Retinal Physician, 2012 -- Combined Cataract Surgery With Pars Plana Vitrectomy: The Vitreoretinal Surgeon’s Perspective
  4. European Glaucoma Society – Terminology and guidelines for glaucoma, 6th Edition | British Journal of Ophthalmology
  5. Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study - ScienceDirect
  6. Glaucoma Physician — Combined Trabecular Microbypass and Goniotomy Effective Recommendations
  7. European Glaucoma Society – Terminology and guidelines for glaucoma, 6th Edition | British Journal of Ophthalmology
  8. Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study - ScienceDirect
  9. Comparison of 5-year outcomes between trabeculectomy combined with phacoemulsification and trabeculectomy followed by phacoemulsification: a retrospective cohort study - PMC

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